Divergent gold-catalysed reactions of cyclopropenylmethyl sulfonamides with tethered heteroaromatics.
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
19 Nov 2019
19 Nov 2019
Historique:
pubmed:
7
11
2019
medline:
7
11
2019
entrez:
6
11
2019
Statut:
ppublish
Résumé
Cyclopropenylmethyl sulfonamides with tethered heteroaromatics have been demonstrated to undergo divergent gold-catalysed cyclisation reactions. A formal dearomative (4+3) cycloaddition takes place with furan-tethered substrates, yielding densely functionalised 5,7-fused heterocycles related to the bioactive curcusone natural products. Indole-tethered substrates display divergent reactivity giving biologically important tetrahydro-β-carbolines via a Friedel-Crafts mechanism.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM