Evaluation of essential oil obtained from

bacterial multidrug resistance bactericidal effect essential oil peppermint

Journal

Infection and drug resistance
ISSN: 1178-6973
Titre abrégé: Infect Drug Resist
Pays: New Zealand
ID NLM: 101550216

Informations de publication

Date de publication:
2019
Historique:
received: 03 06 2019
accepted: 06 08 2019
entrez: 6 11 2019
pubmed: 7 11 2019
medline: 7 11 2019
Statut: epublish

Résumé

Bacterial multidrug resistance currently poses an increasingly serious threat, with important clinical consequences regarding treatment options. In 2017, the WHO released a global list of resistant bacteria, identifying multidrug-resistant (MDR) Gram-negative bacteria such as carbapenem-resistant The novelty presented in this study refers to the evaluation of the volatile oil obtained from the leaves of The essential oil was extracted by steam distillation and tested on six reference bacterial strains and also on the MDR strains collected from patients of the "Pius Brînzeu" Emergency Clinical County Hospital Timișoara. The in vitro antibacterial activity was evaluated by agar disk diffusion method and microdilution method. Testing the antibacterial activity of peppermint oil on both reference strains and isolated MDR strains from hospitalized patients demonstrated its bactericidal effect. Minimum inhibitory concentration (MIC) was lower (20 mg/mL) for The present study highlights the bactericidal activity of

Sections du résumé

BACKGROUND BACKGROUND
Bacterial multidrug resistance currently poses an increasingly serious threat, with important clinical consequences regarding treatment options. In 2017, the WHO released a global list of resistant bacteria, identifying multidrug-resistant (MDR) Gram-negative bacteria such as carbapenem-resistant
PURPOSE OBJECTIVE
The novelty presented in this study refers to the evaluation of the volatile oil obtained from the leaves of
MATERIAL AND METHODS METHODS
The essential oil was extracted by steam distillation and tested on six reference bacterial strains and also on the MDR strains collected from patients of the "Pius Brînzeu" Emergency Clinical County Hospital Timișoara. The in vitro antibacterial activity was evaluated by agar disk diffusion method and microdilution method.
RESULTS RESULTS
Testing the antibacterial activity of peppermint oil on both reference strains and isolated MDR strains from hospitalized patients demonstrated its bactericidal effect. Minimum inhibitory concentration (MIC) was lower (20 mg/mL) for
CONCLUSION CONCLUSIONS
The present study highlights the bactericidal activity of

Identifiants

pubmed: 31686869
doi: 10.2147/IDR.S218141
pii: 218141
pmc: PMC6751511
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2905-2914

Informations de copyright

© 2019 Muntean et al.

Déclaration de conflit d'intérêts

The authors report no conflicts of interest in this work.

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Auteurs

Delia Muntean (D)

Department of Microbiology, "Victor Babes" University of Medicine and Pharmacy, Timisoara 300041, Romania.

Monica Licker (M)

Department of Microbiology, "Victor Babes" University of Medicine and Pharmacy, Timisoara 300041, Romania.

Ersilia Alexa (E)

Department of Food Control, Faculty of Food Processing Technology, Banat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania", Timisoara 300645, Romania.

Iuliana Popescu (I)

Department of Food Control, Faculty of Food Processing Technology, Banat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania", Timisoara 300645, Romania.

Calin Jianu (C)

Department of Food Tehnologies, Faculty of Food Engineering, Banat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania", Timişoara 300645, Romania.

Valentina Buda (V)

Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy, Timisoara 300041, Romania.

Cristina Adriana Dehelean (CA)

Department of Toxicology, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy, Timisoara 300041, Romania.

Roxana Ghiulai (R)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy, Timisoara 300041, Romania.

Florin Horhat (F)

Department of Microbiology, "Victor Babes" University of Medicine and Pharmacy, Timisoara 300041, Romania.

Delia Horhat (D)

Department of ENT, "Victor Babes" University of Medicine and Pharmacy, Timisoara 300041, Romania.

Corina Danciu (C)

Department of Pharmacognosy, "Victor Babes" University of Medicine and Pharmacy, Timisoara 300041, Romania.

Classifications MeSH