Variations in
Ceruloplasmin
Wilson’s disease
primary copper-associated hepatopathy
rhodanine staining
single-nucleotide variation
Journal
Journal of feline medicine and surgery
ISSN: 1532-2750
Titre abrégé: J Feline Med Surg
Pays: England
ID NLM: 100897329
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
pubmed:
7
11
2019
medline:
17
2
2021
entrez:
6
11
2019
Statut:
ppublish
Résumé
Primary copper-associated hepatopathy (PCH) has been reported in young cats. Although our group recently reported a young cat with PCH harbouring single-nucleotide variations in Rhodanine staining was performed to detect hepatic copper accumulation (HCA) in intraoperative liver tissue specimens from 54 cats. In cats with HCA, variations in Based on age, liver histopathological findings and hepatic distribution of accumulated copper, PCH was suspected in 4/54 cats. Sequence analysis of The results of this study suggest that some cats with PCH harbour single-nucleotide variations in
Identifiants
pubmed: 31687873
doi: 10.1177/1098612X19884763
doi:
Substances chimiques
Copper
789U1901C5
Copper-Transporting ATPases
EC 7.2.2.8
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM