Strength Training Increases Conduction Velocity of High-Threshold Motor Units.


Journal

Medicine and science in sports and exercise
ISSN: 1530-0315
Titre abrégé: Med Sci Sports Exerc
Pays: United States
ID NLM: 8005433

Informations de publication

Date de publication:
04 2020
Historique:
pubmed: 7 11 2019
medline: 15 12 2020
entrez: 6 11 2019
Statut: ppublish

Résumé

Motor unit conduction velocity (MUCV) represents the propagation velocity of action potentials along the muscle fibers innervated by individual motor neurons and indirectly reflects the electrophysiological properties of the sarcolemma. In this study, we investigated the effect of a 4-wk strength training intervention on the peripheral properties (MUCV and motor unit action potential amplitude, RMSMU) of populations of longitudinally tracked motor units (MU). The adjustments exhibited by 12 individuals who participated in the training (INT) were compared with 12 controls (CON). Strength training involved ballistic (4 × 10) and sustained (3 × 10) isometric ankle dorsiflexions. Measurement sessions involved the recordings of maximal voluntary isometric force and submaximal isometric ramp contractions, whereas high-density surface EMG was recorded from the tibialis anterior. High-density surface EMG signals were decomposed into individual MU discharge timings, and MU was tracked across the intervention. Maximal voluntary isometric force (+14.1%, P = 0.003) and average MUCV (+3.0%, P = 0.028) increased in the INT group, whereas normalized MU recruitment threshold (RT) decreased (-14.9%, P = 0.001). The slope (rate of change) of the regression between MUCV and MU RT increased only in the INT group (+32.6%, P = 0.028), indicating a progressive greater increase in MUCV for higher-threshold MU. The intercept (initial value) of MUCV did not change after the intervention (P = 0.568). The association between RMSMU and MU RT was not altered by the training. The increase in the rate of change in MUCV as a function of MU RT, but not the initial value of MUCV, suggests that short-term strength training elicits specific adaptations in the electrophysiological properties of the muscle fiber membrane in high-threshold MU.

Identifiants

pubmed: 31688652
doi: 10.1249/MSS.0000000000002196
pii: 00005768-202004000-00022
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

955-967

Références

Folland JP, Williams AG. The adaptations to strength training: morphological and neurological contributions to increased strength. Sports Med. 2007;37(2):145–68.
Van Cutsem M, Duchateau J, Hainaut K. Changes in single motor unit behaviour contribute to the increase in contraction speed after dynamic training in humans. J Physiol. 1998;513(1):295–305.
Nuzzo JL, Barry BK, Jones MD, Gandevia SC, Taylor JL. Effects of four weeks of strength training on the corticomotoneuronal pathway. Med Sci Sports Exerc. 2017;49(11):2286–96.
Weier AT, Pearce AJ, Kidgell DJ. Strength training reduces intracortical inhibition. Acta Physiol. 2012;206(2):109–19.
Blazevich AJ, Gill ND, Deans N, Zhou S. Lack of human muscle architectural adaptation after short-term strength training. Muscle Nerve. 2007;35(1):78–86.
Aagaard P, Andersen JL, Dyhre-Poulsen P, et al. A mechanism for increased contractile strength of human pennate muscle in response to strength training: changes in muscle architecture. J Physiol. 2001;534(2):613–23.
Seynnes OR, de Boer M, Narici MV. Early skeletal muscle hypertrophy and architectural changes in response to high-intensity resistance training. J Appl Physiol. 2007;102(1):368–73.
Balshaw TG, Massey GJ, Maden-Wilkinson TM, Tillin NA, Folland JP. Training-specific functional, neural, and hypertrophic adaptations to explosive- vs. sustained-contraction strength training. J Appl Physiol. 2016;120(11):1364–73.
Del Vecchio A, Casolo A, Negro F, et al. The increase in muscle force after 4 weeks of strength training is mediated by adaptations in motor unit recruitment and rate coding. J Physiol. 2019;597(7):1873–87.
Farina D, Merletti R. Estimation of average muscle fiber conduction velocity from two-dimensional surface EMG recordings. J Neurosci Methods. 2004;134(2):199–208.
Andreassen S, Arendt-Nielsen L. Muscle fibre conduction velocity in motor units of the human anterior tibial muscle: a new size principle parameter. J Physiol. 1987;391(1):561–71.
Farina D, Muhammad W, Fortunato E, Meste O, Merletti R, Rix H. Estimation of single motor unit conduction velocity from surface electromyogram signals detected with linear electrode arrays. Med Biol Eng Comput. 2001;39(2):225–36.
Del Vecchio A, Negro F, Felici F, Farina D. Distribution of muscle fibre conduction velocity for representative samples of motor units in the full recruitment range of the tibialis anterior muscle. Acta Physiol. 2018;222(2):e12930.
Masuda T, De Luca CJ. Recruitment threshold and muscle fiber conduction velocity of single motor units. J Electromyogr Kinesiol. 1991;1(2):116–23.
Holobar A, Zazula D. Multichannel blind source separation using convolution kernel compensation. IEEE Trans Signal Process. 2007;55(9):4487–96.
Hakansson CH. Conduction velocity and amplitude of the action potential as related to circumference in the isolated fibre of frog muscle. Acta Physiol Scand. 1956;37(1):14–34.
Blijham PJ, ter Laak HJ, Schelhaas HJ, van Engelen BG, Stegeman DF, Zwarts MJ. Relation between muscle fiber conduction velocity and fiber size in neuromuscular disorders. J Appl Physiol. 2006;100(6):1837–41.
Methenitis S, Karandreas N, Spengos K, Zaras N, Stasinaki AN, Terzis G. Muscle fiber conduction velocity, muscle fiber composition, and power performance. Med Sci Sports Exerc. 2016;48(9):1761–71.
Plonsey R, Barr CR. Bioelectricity: A Quantitative Approach. New York (NY): Springer Science and Business Media; 2007.
Del Vecchio A, Negro F, Falla D, Bazzucchi I, Farina D, Felici F. Higher muscle fiber conduction velocity and early rate of torque development in chronically strength-trained individuals. J Appl Physiol. 2018;125(4):1218–26.
Del Vecchio A, Negro F, Felici F, Farina D. Associations between motor unit action potential parameters and surface EMG features. J Appl Physiol. 2017;123(4):835–43.
Christiansen D. Molecular stressors underlying exercise training-induced improvements in K+ regulation during exercise and Na+,K+-ATPase adaptation in human skeletal muscle. Acta Physiol. 2019;225(3):e13196.
Allen DG, Lamb GD, Westerblad H. Skeletal muscle fatigue: cellular mechanisms. Physiol Rev. 2008;88(1):287–332.
Farina D, Falla D. Effect of muscle-fiber velocity recovery function on motor unit action potential properties in voluntary contractions. Muscle Nerve. 2008;37(5):650–8.
Duchateau J, Semmler JG, Enoka RM, et al. Training adaptations in the behavior of human motor units. J Appl Physiol. 2006;101(6):1766–75.
Sadoyama T, Masuda T, Miyata H, Katsuta S. Fibre conduction velocity and fibre composition in human vastus lateralis. Eur J Appl Physiol Occup Physiol. 1988;57:767–71.
Martinez-Valdes E, Farina D, Negro F, Del Vecchio A, Falla D. Early motor unit conduction velocity changes to high-intensity interval training versus continuous training. Med Sci Sports Exerc. 2018;50(11):2339–50.
Vila-Chã C, Falla D, Farina D. Motor unit behavior during submaximal contractions following six weeks of either endurance or strength training. J Appl Physiol. 2010;109(5):1455–66.
Holobar A, Minetto MA, Farina D. Accurate identification of motor unit discharge patterns from high-density surface EMG and validation with a novel signal-based performance metric. J Neural Eng. 2014;11(1):016008.
Martinez-Valdes E, Negro F, Laine CM, Falla D, Mayer F, Farina D. Tracking motor units longitudinally across experimental sessions with high-density surface electromyography. J Physiol. 2017;595(5):1479–96.
Farina D, Arendt-nielsen L, Merletti R, Graven-nielsen T. Assessment of single motor unit conduction velocity during sustained contractions of the tibialis anterior muscle with advanced spike triggered averaging. J Neurosci Methods. 2002;115:1–12.
Farina D, Arendt-Nielsen L, Merletti R, Graven-Nielsen T. Effect of experimental muscle pain on motor unit firing rate and conduction velocity. J Neurophysiol. 2004;91(3):1250–9.
Del Vecchio A, Bazzucchi I, Felici F. Variability of estimates of muscle fiber conduction velocity and surface EMG amplitude across subjects and processing intervals. J Electromyogr Kinesiol. 2018;40:102–9.
Cohen J. Statistical Power Analysis for the Behavioral Sciences. Hillsdale (NJ): Lawerence Erlbaum Associates; 1988. 302 p.
Tillin NA, Pain MT, Folland JP. Short-term training for explosive strength causes neural and mechanical adaptations. Exp Physiol. 2012;97(5):630–41.
Bazzucchi I, Riccio ME, Felici F. Tennis players show a lower coactivation of the elbow antagonist muscles during isokinetic exercises. J Electromyogr Kinesiol. 2008;18(5):752–9.
Grosset J-F, Piscione J, Lambertz D, Pérot C. Paired changes in electromechanical delay and musculo-tendinous stiffness after endurance or plyometric training. Eur J Appl Physiol. 2009;105(1):131–9.
Del Vecchio A, Úbeda A, Sartori M, Azorín JM, Felici F, Farina D. Central nervous system modulates the neuromechanical delay in a broad range for the control of muscle force. J Appl Physiol. 2018;125(5):1404–10.
Farina D, Arendt-Nielsen L, Graven-Nielsen T. Effect of temperature on spike-triggered average torque and electrophysiological properties of low-threshold motor units. J Appl Physiol. 2005;99(1):197–203.
Hogrel J-Y. Use of surface EMG for studying motor unit recruitment during isometric linear force ramp. J Electromyogr Kinesiol. 2003;13(5):417–23.
Cadore EL, González-Izal M, Pallarés JG, et al. Muscle conduction velocity, strength, neural activity, and morphological changes after eccentric and concentric training. Scand J Med Sci Sport. 2014;24(5):e343–52.
Clausen T. Na+-K+ pump regulation and skeletal muscle contractility. Physiol Rev. 2003;83(4):1269–324.
Fortune E, Lowery MM. Effect of extracellular potassium accumulation on muscle fiber conduction velocity: a simulation study. Ann Biomed Eng. 2009;37(10):2105–17.
Kössler F, Lange F, Caffier G, Küchler G. External potassium and action potential propagation in rat fast and slow twitch muscles. Gen Physiol Biophys. 1991;10(5):485–98.
Zhang L, Morris KJ, Ng Y-C. Fiber type-specific immunostaining of the Na+,K+–ATPase subunit isoforms in skeletal muscle: age-associated differential changes. Biochim Biophys Acta. 2006;1762(9):783–93.
Klitgaard H, Clausen T. Increased total concentration of Na-K pumps in vastus lateralis muscle of old trained human subjects. J Appl Physiol. 1989;67(6):2491–4.
Green H, Dahly A, Shoemaker K, Goreham C, Bombardier E, Ball-Burnett M. Serial effects of high-resistance and prolonged endurance training on Na+–K+ pump concentration and enzymatic activities in human vastus lateralis. Acta Physiol Scand. 1999;165(2):177–84.
Piitulainen H, Holobar A, Avela J. Changes in motor unit characteristics after eccentric elbow flexor exercise. Scand J Med Sci Sports. 2012;22(3):418–29.
Farina D, Arendt-Nielsen L, Graven-Nielsen T. Spike-triggered average torque and muscle fiber conduction velocity of low-threshold motor units following submaximal endurance contractions. J Appl Physiol. 2005;98(4):1495–502.
Struk A, Lehmann-Horn F, Melzer W. Voltage-dependent calcium release in human malignant hyperthermia muscle fibers. Biophys J. 1998;75(5):2402–10.
Thomas CK, Johansson RS, Bigland-Ritchie B. Pattern of pulses that maximize force output from single human thenar motor units. J Neurophysiol. 1999;82(6):3188–95.
Pope ZK, Hester GM, DeFreitas JM. Action potential amplitude as a non-invasive indicator of motor unit specific hypertrophy. Med Sci Sport Exerc. 2016;48:114.

Auteurs

Dario Farina (D)

Department of Bioengineering, Imperial College London, London, UNITED KINGDOM.

Deborah Falla (D)

Centre of Precision Rehabilitation for Spinal Pain (CPR Spine), School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UNITED KINGDOM.

Ilenia Bazzucchi (I)

Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Rome, ITALY.

Francesco Felici (F)

Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Rome, ITALY.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH