Influence of cognitive reserve in schizophrenia: A systematic review.
Cognitive rehabilitation
Cognitive reserve
Schizophrenia
Journal
Neuroscience and biobehavioral reviews
ISSN: 1873-7528
Titre abrégé: Neurosci Biobehav Rev
Pays: United States
ID NLM: 7806090
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
10
06
2019
revised:
10
10
2019
accepted:
26
10
2019
pubmed:
7
11
2019
medline:
29
12
2020
entrez:
6
11
2019
Statut:
ppublish
Résumé
To perform a systematic review of the influence of sociobehavioural indicators of cognitive reserve (CR) in the risk of schizophrenia, the clinical manifestations of the disease, and cognitive intervention programs (CRT) carried out with these patients. A cross search was made by two independent reviewers in Pubmed and PsycINFO databases using keywords "schizophrenia" and "cognitive reserve." Twenty-one studies which analyzed different CR proxies were selected and the level of evidence was classified according to the Oxford Centre for Evidence-Based Medicine. People with higher CR may have a lower risk of developing schizophrenia and a later onset of disease. In addition, they present better neuropsychological and functional performance in the illness course. However, the suspected influence of CR on the effectiveness of CRT in patients with schizophrenia is currently unresolved. Our findings suggest that higher CR delays the clinical diagnosis threshold and severity of the symptoms in patients with schizophrenia. However, effect of singular sociobehavioral measures on clinical expression and benefits of intervention program need further investigation.
Identifiants
pubmed: 31689453
pii: S0149-7634(19)30481-6
doi: 10.1016/j.neubiorev.2019.10.019
pii:
doi:
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
149-159Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.