Oligodendroglioma with Neuronal Differentiation in Two Boxer Dogs.


Journal

Journal of comparative pathology
ISSN: 1532-3129
Titre abrégé: J Comp Pathol
Pays: England
ID NLM: 0102444

Informations de publication

Date de publication:
Oct 2019
Historique:
received: 27 05 2019
revised: 22 07 2019
accepted: 07 08 2019
entrez: 7 11 2019
pubmed: 7 11 2019
medline: 24 3 2020
Statut: ppublish

Résumé

Two cases of high-grade glioma comprising sheets of oligodendroglial cells multifocally disrupted by regions of remarkable neuronal differentiation are described. These tumours morphologically resemble 'oligodendroglioma with ganglioglioma-like maturation', a rare tumour of man, but appear to be phenotypically more aggressive. Neuronal markers (synaptophysin, neuron-specific enolase and βIII-tubulin) effectively highlight neuronal elements within these tumours and could potentially help to further investigate the prevalence and biological significance of neuronal differentiation in canine oligodendroglioma.

Identifiants

pubmed: 31690408
pii: S0021-9975(19)30264-6
doi: 10.1016/j.jcpa.2019.08.003
pii:
doi:

Substances chimiques

Biomarkers 0
Synaptophysin 0
Tubulin 0
Phosphopyruvate Hydratase EC 4.2.1.11

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

11-16

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

I Cornax (I)

Comparative Pathology Shared Resource, Masonic Cancer Center, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA.

G E Pluhar (GE)

Department of Veterinary Clinical Sciences, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA.

H B Clark (HB)

Department of Laboratory Medicine and Pathology, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA.

M G O'Sullivan (MG)

Comparative Pathology Shared Resource, Masonic Cancer Center, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA; Department of Veterinary Population Medicine, College of Veterinary Medicine, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA. Electronic address: gos@umn.edu.

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Classifications MeSH