Association between glycated hemoglobin (HbA1c) and the lipid profile in patients with type 2 diabetes mellitus at a tertiary care hospital: a retrospective study.

DMT2 dyslipidemia glycated hemoglobin glycemic control lipid profile

Journal

Diabetes, metabolic syndrome and obesity : targets and therapy
ISSN: 1178-7007
Titre abrégé: Diabetes Metab Syndr Obes
Pays: New Zealand
ID NLM: 101515585

Informations de publication

Date de publication:
2019
Historique:
received: 07 07 2019
accepted: 20 08 2019
entrez: 8 11 2019
pubmed: 7 11 2019
medline: 7 11 2019
Statut: epublish

Résumé

To investigate the association between glycated hemoglobin (HbA1c) and the lipid profile in patients with type 2 diabetes mellitus (T2DM) at a tertiary care hospital in Jeddah, Saudi Arabia (SA). The present retrospective cross-sectional study was accomplished at the Faculty of Medicine, King Abdulaziz University (KAU), Jeddah, SA, between April and July 2018. There were 206 T2DM patients selected for the study (141 females and 65 males), and the data were collected through a review of the electronic profiles of patients by using the medical electronic file system used at the KAU Hospital. Biochemical data such as fasting plasma glucose (FPG), HbA1c and lipid profile, along with the patient's age, BMI and gender, were also taken from the electronic file system. The inclusion criteria allowed for only patients who were regularly seeing their physician and whose electronic file was up to date. The participants' data were analyzed gender-wise. The females had significantly higher values for BMI ( The glycated Hb was associated with TGs, and no significant association was found with age, BMI, TC, LDL-C, HDL-C and FPG levels.

Sections du résumé

BACKGROUND BACKGROUND
To investigate the association between glycated hemoglobin (HbA1c) and the lipid profile in patients with type 2 diabetes mellitus (T2DM) at a tertiary care hospital in Jeddah, Saudi Arabia (SA).
METHODS METHODS
The present retrospective cross-sectional study was accomplished at the Faculty of Medicine, King Abdulaziz University (KAU), Jeddah, SA, between April and July 2018. There were 206 T2DM patients selected for the study (141 females and 65 males), and the data were collected through a review of the electronic profiles of patients by using the medical electronic file system used at the KAU Hospital. Biochemical data such as fasting plasma glucose (FPG), HbA1c and lipid profile, along with the patient's age, BMI and gender, were also taken from the electronic file system. The inclusion criteria allowed for only patients who were regularly seeing their physician and whose electronic file was up to date.
RESULTS RESULTS
The participants' data were analyzed gender-wise. The females had significantly higher values for BMI (
CONCLUSION CONCLUSIONS
The glycated Hb was associated with TGs, and no significant association was found with age, BMI, TC, LDL-C, HDL-C and FPG levels.

Identifiants

pubmed: 31695459
doi: 10.2147/DMSO.S222271
pii: 222271
pmc: PMC6718241
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1639-1644

Informations de copyright

© 2019 Alzahrani et al.

Déclaration de conflit d'intérêts

Financial support was received from King Abdulaziz University (DSR), Jeddah, under grant No. (D-063-140-1440). The authors report no other conflicts of interest in this work.

Références

J Lipid Res. 1996 Apr;37(4):693-707
pubmed: 8732771
J Res Med Sci. 2015 Jan;20(1):40-6
pubmed: 25767521
Ther Adv Endocrinol Metab. 2017 Apr;8(4):51-57
pubmed: 28507727
Cureus. 2017 Jun 13;9(6):e1347
pubmed: 28713663
Diabetes Ther. 2016 Jun;7(2):203-19
pubmed: 27056202
Am Heart J. 2006 Jul;152(1):27-38
pubmed: 16824829
Acta Diabetol. 2007 Dec;44(4):193-200
pubmed: 17786383
J Am Med Dir Assoc. 2005 May-Jun;6(3):200-4
pubmed: 15894250
Indian J Endocrinol Metab. 2013 Nov;17(6):1030-9
pubmed: 24381880
Diabetes Care. 2010 Jan;33 Suppl 1:S62-9
pubmed: 20042775
Lipids Health Dis. 2014 Dec 06;13:183
pubmed: 25481115
Diabetes Care. 2015 Oct;38(10):1930-6
pubmed: 26307606
J Womens Health (Larchmt). 2006 Jan-Feb;15(1):54-6
pubmed: 16417419

Auteurs

Sami Hamdan Alzahrani (SH)

Family Medicine Department, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Mukhtiar Baig (M)

Department of Clinical Biochemistry, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.

Mooataz Mohammed Aashi (MM)

Pediatric Department, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

Faisal Khaled Al-Shaibi (FK)

Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Dalya Abdulrahman Alqarni (DA)

Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Wael Hassan Bakhamees (WH)

Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Classifications MeSH