Cardiovascular risk of electronic cigarettes: a review of preclinical and clinical studies.


Journal

Cardiovascular research
ISSN: 1755-3245
Titre abrégé: Cardiovasc Res
Pays: England
ID NLM: 0077427

Informations de publication

Date de publication:
01 01 2020
Historique:
received: 05 04 2019
revised: 08 08 2019
accepted: 04 10 2019
pubmed: 7 11 2019
medline: 26 8 2020
entrez: 8 11 2019
Statut: ppublish

Résumé

Cigarette smoking is the most preventable risk factor related to cardiovascular morbidity and mortality. Tobacco usage has declined in recent years; however, the use of alternative nicotine delivery methods, particularly e-cigarettes, has increased exponentially despite limited data on their short- and long-term safety and efficacy. Due to their unique properties, the impact of e-cigarettes on cardiovascular physiology is not fully known. Here, we summarize both preclinical and clinical data extracted from short- and long-term studies on the cardiovascular effects of e-cigarette use. Current findings support that e-cigarettes are not a harm-free alternative to tobacco smoke. However, the data are primarily derived from acute studies. The impact of chronic e-cigarette exposure is essentially unstudied. To explore the uniqueness of e-cigarettes, we contemplate the cardiovascular effects of individual e-cigarette constituents. Overall, data suggest that exposure to e-cigarettes could be a potential cardiovascular health concern. Further preclinical research and randomized trials are needed to expand basic and clinical investigations before considering e-cigarettes safe alternatives to conventional cigarettes.

Identifiants

pubmed: 31696222
pii: 5613736
doi: 10.1093/cvr/cvz256
pmc: PMC8204488
doi:

Substances chimiques

Aldehydes 0
E-Cigarette Vapor 0
Flavoring Agents 0
Metals 0
Oxidants 0
Nicotine 6M3C89ZY6R

Types de publication

Journal Article Research Support, N.I.H., Extramural Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

40-50

Subventions

Organisme : NIA NIH HHS
ID : R01 AG057046
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL139348
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.

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Auteurs

Nicholas D Buchanan (ND)

Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, 473 W. 12th Avenue, Columbus, OH 43210, USA.
College of Nursing, The Ohio State University, Columbus, OH, USA.

Jacob A Grimmer (JA)

Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, 473 W. 12th Avenue, Columbus, OH 43210, USA.
College of Nursing, The Ohio State University, Columbus, OH, USA.

Vineeta Tanwar (V)

Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, 473 W. 12th Avenue, Columbus, OH 43210, USA.
College of Nursing, The Ohio State University, Columbus, OH, USA.

Neill Schwieterman (N)

Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, 473 W. 12th Avenue, Columbus, OH 43210, USA.
College of Nursing, The Ohio State University, Columbus, OH, USA.

Peter J Mohler (PJ)

Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, 473 W. 12th Avenue, Columbus, OH 43210, USA.
Department of Physiology and Cell Biology, The Ohio State University College of Medicine and Wexner Medical Center, Columbus, OH, USA.

Loren E Wold (LE)

Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, 473 W. 12th Avenue, Columbus, OH 43210, USA.
College of Nursing, The Ohio State University, Columbus, OH, USA.
Department of Physiology and Cell Biology, The Ohio State University College of Medicine and Wexner Medical Center, Columbus, OH, USA.

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