Comparison of continuous 24-h and 14-day monitoring for detection of otherwise unknown atrial fibrillation: a registry to identify Japanese concealed atrial fibrillation (REAL-AF)-based study.
Administration, Oral
Aged
Aged, 80 and over
Anticoagulants
/ administration & dosage
Atrial Fibrillation
/ diagnosis
Early Diagnosis
Electrocardiography, Ambulatory
Female
Heart Rate
Humans
Japan
/ epidemiology
Male
Predictive Value of Tests
Prevalence
Prognosis
Prospective Studies
Registries
Time Factors
Atrial fibrillation
Continuous monitoring
Oral anticoagulant therapy
Journal
Heart and vessels
ISSN: 1615-2573
Titre abrégé: Heart Vessels
Pays: Japan
ID NLM: 8511258
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
14
08
2019
accepted:
01
11
2019
pubmed:
7
11
2019
medline:
15
12
2020
entrez:
8
11
2019
Statut:
ppublish
Résumé
Early detection of atrial fibrillation (AF) is desirable for preventing strokes. Not only does AF often go undetected in patients being followed up for various disease conditions, but the optimal detection method also remains to be elucidated. In a prospective observational study of 24-h Holter monitoring versus 14-day external loop recording performed for detection of previously undiagnosed AF in 868 Japanese outpatients (aged 75 ± 6 years), with a CHA2DS2-vasc score ≥ 1, but no prior AF episodes, AF was detected during the initial monitoring period in 16 (1.8%) patients, in 7 (1.1% [7/645]) by 24-h monitoring and 9 (4.0% [9/223]) by 14-day monitoring (P = 0.005), and overall in 32 (3.7%) during the 1-year study period. Absence of a beta-blocker therapy and the serum N-terminal pro-brain natriuretic peptide level were independent predictors of a new detection of AF. Oral anticoagulation (OAC) therapy was given to 22 (69%) of the 32 patients in whom AF was detected, and no difference in the incidence of subsequent major adverse events was found between the patients managed with and without oral OAC therapy. Previously unknown AF was documented at a prevalence of 3.7% per year among Japanese with a notable CHA
Identifiants
pubmed: 31696252
doi: 10.1007/s00380-019-01535-6
pii: 10.1007/s00380-019-01535-6
doi:
Substances chimiques
Anticoagulants
0
Types de publication
Comparative Study
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
689-698Références
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