Setting research priorities on multiple micronutrient supplementation in pregnancy.
low- and middle-income countries
micronutrients
pregnancy
research priorities
supplementation
Journal
Annals of the New York Academy of Sciences
ISSN: 1749-6632
Titre abrégé: Ann N Y Acad Sci
Pays: United States
ID NLM: 7506858
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
12
08
2019
revised:
09
10
2019
accepted:
16
10
2019
pubmed:
7
11
2019
medline:
9
7
2020
entrez:
8
11
2019
Statut:
ppublish
Résumé
Prenatal micronutrient deficiencies are associated with negative maternal and birth outcomes. Multiple micronutrient supplementation (MMS) during pregnancy is a cost-effective intervention to reduce these adverse outcomes. However, important knowledge gaps remain in the implementation of MMS interventions. The Child Health and Nutrition Research Initiative (CHNRI) methodology was applied to inform the direction of research and investments needed to support the implementation of MMS interventions for pregnant women in low- and middle-income countries (LMIC). Following CHNRI methodology guidelines, a group of international experts in nutrition and maternal health provided and ranked the research questions that most urgently need to be resolved for prenatal MMS interventions to be successfully implemented. Seventy-three research questions were received, analyzed, and reorganized, resulting in 35 consolidated research questions. These were scored against four criteria, yielding a priority ranking where the top 10 research options focused on strategies to increase antenatal care attendance and MMS adherence, methods needed to identify populations more likely to benefit from MMS interventions and some discovery issues (e.g., potential benefit of extending MMS through lactation). This exercise prioritized 35 discrete research questions that merit serious consideration for the potential of MMS during pregnancy to be optimized in LMIC.
Identifiants
pubmed: 31696532
doi: 10.1111/nyas.14267
pmc: PMC7186835
doi:
Substances chimiques
Micronutrients
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
76-88Subventions
Organisme : Medical Research Council
ID : MC_PC_MR/R019177/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_U123292701
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P012019/1
Pays : United Kingdom
Informations de copyright
© 2019 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals, Inc. on behalf of New York Academy of Sciences.
Références
Croat Med J. 2008 Dec;49(6):720-33
pubmed: 19090596
Ann N Y Acad Sci. 2019 May;1444(1):6-21
pubmed: 31134643
J Glob Health. 2014 Dec;4(2):020413
pubmed: 25520803
Public Health Nutr. 2009 Mar;12(3):389-96
pubmed: 18426636
Lancet Glob Health. 2017 Nov;5(11):e1090-e1100
pubmed: 29025632
Ann N Y Acad Sci. 2019 May;1444(1):3-5
pubmed: 31032931
Nat Rev Endocrinol. 2016 May;12(5):274-89
pubmed: 27032981
Lancet Glob Health. 2019 Jul;7(7):e849-e860
pubmed: 31103470
J Glob Health. 2017 Jun;7(1):011004
pubmed: 28685049
Public Health Nutr. 2016 Mar;19(4):732-42
pubmed: 26022914
J Nutr. 2019 Jul 1;149(7):1222-1229
pubmed: 31131412
Ann N Y Acad Sci. 2019 May;1444(1):35-51
pubmed: 31134641
Ann N Y Acad Sci. 2019 May;1444(1):22-34
pubmed: 31094004
Lancet Neurol. 2016 Nov;15(12):1285-1294
pubmed: 27751558