Ancient Rome: A genetic crossroads of Europe and the Mediterranean.
Journal
Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511
Informations de publication
Date de publication:
08 11 2019
08 11 2019
Historique:
received:
10
07
2019
accepted:
04
10
2019
entrez:
9
11
2019
pubmed:
9
11
2019
medline:
9
4
2020
Statut:
ppublish
Résumé
Ancient Rome was the capital of an empire of ~70 million inhabitants, but little is known about the genetics of ancient Romans. Here we present 127 genomes from 29 archaeological sites in and around Rome, spanning the past 12,000 years. We observe two major prehistoric ancestry transitions: one with the introduction of farming and another prior to the Iron Age. By the founding of Rome, the genetic composition of the region approximated that of modern Mediterranean populations. During the Imperial period, Rome's population received net immigration from the Near East, followed by an increase in genetic contributions from Europe. These ancestry shifts mirrored the geopolitical affiliations of Rome and were accompanied by marked interindividual diversity, reflecting gene flow from across the Mediterranean, Europe, and North Africa.
Identifiants
pubmed: 31699931
pii: 366/6466/708
doi: 10.1126/science.aay6826
pmc: PMC7093155
mid: NIHMS1551077
doi:
Types de publication
Historical Article
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
708-714Subventions
Organisme : NLM NIH HHS
ID : T15 LM007033
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007828
Pays : United States
Organisme : NLM NIH HHS
ID : T32 LM012409
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
Références
Nat Commun. 2018 Sep 11;9(1):3547
pubmed: 30206220
Nat Genet. 2016 Jan;48(1):94-100
pubmed: 26642242
Nature. 2018 Mar 8;555(7695):197-203
pubmed: 29466330
Nature. 2015 Dec 24;528(7583):499-503
pubmed: 26595274
PLoS Genet. 2012 Jan;8(1):e1002453
pubmed: 22291602
Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):6886-91
pubmed: 27274049
Genome Res. 2009 Sep;19(9):1655-64
pubmed: 19648217
Nat Ecol Evol. 2020 Mar;4(3):334-345
pubmed: 32094539
Nature. 2015 Jun 11;522(7555):167-72
pubmed: 26062507
Nature. 2014 Sep 18;513(7518):409-13
pubmed: 25230663
Sci Rep. 2018 Oct 5;8(1):14879
pubmed: 30291256
Nature. 2017 Aug 10;548(7666):214-218
pubmed: 28783727
Nature. 2015 Jun 11;522(7555):207-11
pubmed: 25731166
Sci Adv. 2019 Sep 04;5(9):eaaw3492
pubmed: 31517044
Nature. 2016 May 02;534(7606):200-5
pubmed: 27135931
Am J Phys Anthropol. 2007 Apr;132(4):510-9
pubmed: 17205550
Am J Hum Genet. 2019 May 2;104(5):977-984
pubmed: 31006515
Genetics. 2012 Nov;192(3):1065-93
pubmed: 22960212
Sci Rep. 2018 Dec 4;8(1):17567
pubmed: 30514893
Science. 2019 Mar 15;363(6432):1230-1234
pubmed: 30872528