Malignant Chondroid Syringoma: A Report of Two Cases with a Sarcomatous Mesenchymal Component.
Adnexal neoplasms
Carcinosarcoma
Chondroid syringoma
Malignant mixed tumour
Skin
Journal
Dermatopathology (Basel, Switzerland)
ISSN: 2296-3529
Titre abrégé: Dermatopathology (Basel)
Pays: Switzerland
ID NLM: 101651125
Informations de publication
Date de publication:
Historique:
received:
16
11
2018
accepted:
19
11
2018
entrez:
9
11
2019
pubmed:
9
11
2019
medline:
9
11
2019
Statut:
epublish
Résumé
Malignant chondroid syringoma (MCS; malignant mixed tumour) is a rare neoplasm typically arising on the extremities and trunk. We are report 2 unique cases of MCS, one occurring on the scalp of a 78-year-old man and the other on the trunk of a 72-year-old woman. Both tumours harboured malignant epithelial and malignant mesenchymal components. The latter was represented by liposarcoma in the first case. The malignant components of the second tumour comprised spindle cell squamous cell carcinoma (SCC) and osteosarcoma. Origin from a pre-existing benign chondroid syringoma was clearly evident in both neoplasms. The presence of heterologous malignant mesenchymal components, however, is hitherto unreported in the context of MCS, while a spindle cell SCC component is exceptionally rare. The 2 cases presented herein highlight an expanded morphological spectrum of MCS, with resultant blurring of the boundaries between MCS and cutaneous carcinosarcoma.
Identifiants
pubmed: 31700847
doi: 10.1159/000495610
pii: dpa-0006-0077
pmc: PMC6827459
doi:
Types de publication
Case Reports
Langues
eng
Pagination
77-84Informations de copyright
Copyright © 2019 by S. Karger AG, Basel.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to declare.
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