Increased risk of eczema after joint replacement: A population-based retrospective cohort study.
Aged
Arthroplasty, Replacement
/ adverse effects
Case-Control Studies
Comorbidity
Dermatitis, Allergic Contact
/ epidemiology
Eczema
/ epidemiology
Female
Humans
Incidence
Joint Prosthesis
/ adverse effects
Longitudinal Studies
Male
Metals
/ adverse effects
Middle Aged
Proportional Hazards Models
Retrospective Studies
Risk Factors
Journal
Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
entrez:
9
11
2019
pubmed:
9
11
2019
medline:
26
11
2019
Statut:
ppublish
Résumé
There are very few reports of eczema and other prosthetic-related allergic skin complications following arthroplasty. We aimed to assess the risk of eczema after joint replacement.We performed a retrospective population-based cohort study in 2024 joint replacement patients using the Longitudinal Health Insurance Database. For comparison, 8096 controls were selected, with 4 control subjects for each joint replacement patient matched for age, sex, and index year, to assess eczema risk. We examined 14-year cumulative eczema incidence associated with age, sex, immunity, disease history, and joint replacement location.Eczema rates in the joint replacement patients were 38% higher than in the control group (57.90 vs 41.84 per 1000 person-years, respectively). Compared with the control group, joint replacement patients showed a 1.35-fold increased risk of eczema according to the multivariable Cox model (95% Confidence interval [CI] = 1.23-1.49). Knee replacement patients had higher eczema risk compared with the control group (Hazard ratio [HR] = 1.45, 95% CI = 1.33-1.70). Stratified by study period, the joint replacement cohort had a higher eczema risk after the 3-month follow-up.Our study revealed that joint arthroplasty increased risk of eczema in this 14-year follow-up study, and this was not related to personal atopic history or gender.
Identifiants
pubmed: 31702670
doi: 10.1097/MD.0000000000017914
pii: 00005792-201911080-00064
pmc: PMC6855572
doi:
Substances chimiques
Metals
0
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
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