Novel Gd


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
08 11 2019
Historique:
received: 01 02 2019
accepted: 14 10 2019
entrez: 10 11 2019
pubmed: 11 11 2019
medline: 31 10 2020
Statut: epublish

Résumé

Optical fibers hold promise for accurate dosimetry in small field proton therapy due to their superior spatial resolution and the lack of significant Cerenkov contamination in proton beams. One known drawback for most scintillation detectors is signal quenching in areas of high linear energy transfer, as is the case in the Bragg peak region of a proton beam. In this study, we investigated the potential of innovative optical fiber bulk materials using the sol-gel technique for dosimetry in proton therapy. This type of glass is made of amorphous silica (SiO[Formula: see text]) and is doped with Gd[Formula: see text] ions and possesses very interesting light emission properties with a luminescence band around 314 nm when exposed to protons. The fibers were manufactured at the University of Lille and tested at the TRIUMF Proton Therapy facility with 8.2-62.9 MeV protons and 2-6 nA of extracted beam current. Dose-rate dependence and quenching were measured and compared to other silica-based fibers also made by sol-gel techniques and doped with Ce[Formula: see text] and Cu[Formula: see text]. The three fibers present strong luminescence in the UV (Gd) or visible (Cu,Ce) under irradiation, with the emission intensities related directly to the proton flux. In addition, the 0.5 mm diameter Gd[Formula: see text]-doped fiber shows superior resolution of the Bragg peak, indicating significantly reduced quenching in comparison to the Ce[Formula: see text] and Cu[Formula: see text] fibers with a Birks' constant, k[Formula: see text], of (0.0162 [Formula: see text] 0.0003) cm/MeV in comparison to (0.0333 [Formula: see text] 0.0006) cm/MeV and (0.0352 [Formula: see text] 0.0003) cm/MeV, respectively. To our knowledge, this is the first report of such an interesting k[Formula: see text] for a silica-based optical fiber material, showing clearly that this fiber presents lower quenching than common plastic scintillators. This result demonstrates the high potential of this inorganic fiber material for proton therapy dosimetry.

Identifiants

pubmed: 31704964
doi: 10.1038/s41598-019-52608-5
pii: 10.1038/s41598-019-52608-5
pmc: PMC6841944
doi:

Substances chimiques

Protons 0
Silicon Dioxide 7631-86-9
Gadolinium AU0V1LM3JT

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

16376

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Auteurs

C Hoehr (C)

TRIUMF, 4004 Wesbrook Mall, Vancouver, Canada. choehr@triumf.ca.

A Morana (A)

Univ-Lyon, Laboratoire H. Curien, F-42000, Saint-Etienne, France.

O Duhamel (O)

CEA, DAM, DIF, Arpajon, F-91297, France.

B Capoen (B)

Univ-Lille, UMR 78523-PhLAM - Physique des Lasers, Atomes et Molecules, F-59000, Lille, France.

M Trinczek (M)

TRIUMF, 4004 Wesbrook Mall, Vancouver, Canada.

P Paillet (P)

CEA, DAM, DIF, Arpajon, F-91297, France.

C Duzenli (C)

British Columbia Cancer, Vancouver, Canada.
University of British Columbia, Physics and Astronomy, Vancouver, Canada.

M Bouazaoui (M)

Univ-Lille, UMR 78523-PhLAM - Physique des Lasers, Atomes et Molecules, F-59000, Lille, France.

G Bouwmans (G)

Univ-Lille, UMR 78523-PhLAM - Physique des Lasers, Atomes et Molecules, F-59000, Lille, France.

A Cassez (A)

Univ-Lille, UMR 78523-PhLAM - Physique des Lasers, Atomes et Molecules, F-59000, Lille, France.

Y Ouerdane (Y)

Univ-Lyon, Laboratoire H. Curien, F-42000, Saint-Etienne, France.

A Boukenter (A)

Univ-Lyon, Laboratoire H. Curien, F-42000, Saint-Etienne, France.

H El Hamzaoui (H)

Univ-Lille, UMR 78523-PhLAM - Physique des Lasers, Atomes et Molecules, F-59000, Lille, France.

S Girard (S)

Univ-Lyon, Laboratoire H. Curien, F-42000, Saint-Etienne, France.

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Classifications MeSH