Effect of exogenous progesterone administration on cigarette smoking-related symptomology in oral contraceptive users who smoke.
Cigarette smoking-related symptomatology
Progesterone
Sex hormones
Women’s health
Journal
Addictive behaviors
ISSN: 1873-6327
Titre abrégé: Addict Behav
Pays: England
ID NLM: 7603486
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
28
06
2019
revised:
02
09
2019
accepted:
25
09
2019
pubmed:
11
11
2019
medline:
23
1
2021
entrez:
10
11
2019
Statut:
ppublish
Résumé
Cigarette smoking-related symptomatology (e.g., craving; SRS) is linked to relapse after a quit attempt. SRS varies by menstrual phase, possibly due to variations in sex hormones (e.g., progesterone), though much of the research to-date has relied on observations from the menstrual cycle acting as a proxy for hormone levels. The goal of this study was to examine the effect of exogenous progesterone on SRS during ad libitum smoking and following overnight abstinence. Oral contraceptive users who smoked completed two 9-day crossover testing periods (7 days of ad libitum smoking and 2 days following overnight abstinence) while taking double-blind active/placebo exogenous progesterone. Participants completed questionnaires to measure SRS. The effect of exogenous progesterone and endogenous hormones (progesterone, estradiol, and progesterone-to-estradiol [P/E
Identifiants
pubmed: 31706140
pii: S0306-4603(19)30802-0
doi: 10.1016/j.addbeh.2019.106148
pii:
doi:
Substances chimiques
Contraceptives, Oral
0
Progesterone
4G7DS2Q64Y
Estradiol
4TI98Z838E
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
106148Subventions
Organisme : NIDA NIH HHS
ID : R01 DA008075
Pays : United States
Informations de copyright
Copyright © 2019. Published by Elsevier Ltd.