Monostotic fibrous dysplasia at C7 treated with vertebroplasty: a case report and review of the literature.


Journal

World journal of surgical oncology
ISSN: 1477-7819
Titre abrégé: World J Surg Oncol
Pays: England
ID NLM: 101170544

Informations de publication

Date de publication:
09 Nov 2019
Historique:
received: 22 06 2019
accepted: 30 09 2019
entrez: 11 11 2019
pubmed: 11 11 2019
medline: 28 4 2020
Statut: epublish

Résumé

Monostotic fibrous dysplasia (MFD) involving the spine is rare, and the treatment options are controversial. Surgery is needed when patients suffer from persistent pain, spinal cord compression/injury, and vertebral collapse/instability. Treatment methods include biopsy/observation, corpectomy with instrumented fusion, posterior fusion, vertebroplasty (VP), curettage and bone graft, and complete removal of the vertebra with a combined anterior and posterior fusion procedure. The patient was a 56-year-old woman with a 2-year history of neck pain. No obvious abnormalities were detected on neurological or physical examination, and laboratory findings were all within normal limits. An imaging examination suggested a C7 vertebral bone tumor. The patient refused to continue conservative observation treatment and requested surgery. Open VP of the C7 vertebral body was carried out, and her postoperative neck pain was completely relieved. The postoperative pathological results supported the diagnosis of fibrous dysplasia, and the patient was ultimately diagnosed with MFD. At the 12-month follow-up visit, the patient reported no clinical symptoms, and no signs of tumor recurrence were detected. VP can relieve pain while stabilizing the spine. Thus, the surgical treatment of MFD vertebral lesions by VP is a valuable option.

Sections du résumé

BACKGROUND BACKGROUND
Monostotic fibrous dysplasia (MFD) involving the spine is rare, and the treatment options are controversial. Surgery is needed when patients suffer from persistent pain, spinal cord compression/injury, and vertebral collapse/instability. Treatment methods include biopsy/observation, corpectomy with instrumented fusion, posterior fusion, vertebroplasty (VP), curettage and bone graft, and complete removal of the vertebra with a combined anterior and posterior fusion procedure.
CASE PRESENTATION METHODS
The patient was a 56-year-old woman with a 2-year history of neck pain. No obvious abnormalities were detected on neurological or physical examination, and laboratory findings were all within normal limits. An imaging examination suggested a C7 vertebral bone tumor. The patient refused to continue conservative observation treatment and requested surgery. Open VP of the C7 vertebral body was carried out, and her postoperative neck pain was completely relieved. The postoperative pathological results supported the diagnosis of fibrous dysplasia, and the patient was ultimately diagnosed with MFD. At the 12-month follow-up visit, the patient reported no clinical symptoms, and no signs of tumor recurrence were detected.
CONCLUSION CONCLUSIONS
VP can relieve pain while stabilizing the spine. Thus, the surgical treatment of MFD vertebral lesions by VP is a valuable option.

Identifiants

pubmed: 31706319
doi: 10.1186/s12957-019-1717-2
pii: 10.1186/s12957-019-1717-2
pmc: PMC6842499
doi:

Substances chimiques

Bone Cements 0

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

186

Références

Neurol India. 2008 Oct-Dec;56(4):497-8
pubmed: 19127059
J Bone Joint Surg Am. 2011 Jul 6;93(13):e74
pubmed: 21776559
Radiology. 2003 Feb;226(2):366-72
pubmed: 12563127
J Bone Joint Surg Am. 1990 Jun;72(5):781-3
pubmed: 2355045
Neurosciences (Riyadh). 2011 Jan;16(1):76-7
pubmed: 21206451
Acta Chir Scand. 1956 Dec 9;111(6):490-4
pubmed: 13381372
J Bone Miner Res. 2008 Nov;23(11):1731-40
pubmed: 18597624
Spine (Phila Pa 1976). 2009 Oct 15;34(22 Suppl):S118-27
pubmed: 19829271
AJNR Am J Neuroradiol. 2004 Oct;25(9):1583-8
pubmed: 15502142
Spine (Phila Pa 1976). 1997 Dec 15;22(24 Suppl):38S-42S
pubmed: 9431643
J Craniovertebr Junction Spine. 2010 Jul;1(2):118-21
pubmed: 21572633
Eur Spine J. 1992 Sep;1(2):137-9
pubmed: 20054961
Br J Neurosurg. 2004 Oct;18(5):527-33
pubmed: 15799160
Spine (Phila Pa 1976). 1989 Feb;14(2):243-5
pubmed: 2922645
Spine (Phila Pa 1976). 2011 Oct 15;36(22):E1485-8
pubmed: 21358488
Eur Spine J. 2007 Dec;16 Suppl 3:250-4
pubmed: 17665224
World J Surg Oncol. 2014 Nov 18;12:349
pubmed: 25407316
N Engl J Med. 1991 Dec 12;325(24):1688-95
pubmed: 1944469
J Bone Joint Surg Am. 2005 Aug;87(8):1848-64
pubmed: 16085630
Radiology. 1996 Apr;199(1):241-7
pubmed: 8633152
J Bone Joint Surg Am. 2004 Mar;86(3):531-7
pubmed: 14996879
Am J Med Genet. 2001 Feb 1;98(4):290-3
pubmed: 11170069
J Bone Joint Surg Am. 2016 Feb 3;98(3):211-9
pubmed: 26842411
J Neurosurg Spine. 2005 Sep;3(3):234-7
pubmed: 16235708
Bone. 1999 Aug;25(2 Suppl):85S-90S
pubmed: 10458283
Acta Orthop Belg. 2012 Aug;78(4):512-8
pubmed: 23019785
Spine (Phila Pa 1976). 2013 Nov 1;38(23):2016-22
pubmed: 23970113
Spine (Phila Pa 1976). 2008 Nov 15;33(24):E933-5
pubmed: 19011535
Acta Orthop Belg. 2007 Feb;73(1):96-101
pubmed: 17441665
Int J Spine Surg. 2018 Dec 21;12(6):659-664
pubmed: 30619668
J Pediatr Orthop B. 2003 May;12(3):155-77
pubmed: 12703030
Eur Spine J. 1995;4(6):372-4
pubmed: 8983661

Auteurs

Xin Xin (X)

Department of Orthopaedics, Ankang Center Hospital, Ankang, 725000, Shaanxi Province, People's Republic of China.

Jianhong Feng (J)

Department of Orthopaedics, Ankang Center Hospital, Ankang, 725000, Shaanxi Province, People's Republic of China.

Chen Yue (C)

Department of Orthopaedics, Ankang Center Hospital, Ankang, 725000, Shaanxi Province, People's Republic of China.

Tao Jin (T)

Department of Orthopaedics, Ankang Center Hospital, Ankang, 725000, Shaanxi Province, People's Republic of China.

Xinxin Liu (X)

Department of Magnetic Resonance Imaging, Hong Hui Hospital of Xi'an Jiaotong University, Xi'an, 710054, Shaanxi Province, People's Republic of China. liuxinxinfly2008@163.com.

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Classifications MeSH