Suprascapular nerve neuropathy leads to supraspinatus tendon degeneration.
Journal
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
ISSN: 1436-2023
Titre abrégé: J Orthop Sci
Pays: Japan
ID NLM: 9604934
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
23
04
2019
revised:
20
08
2019
accepted:
20
09
2019
pubmed:
14
11
2019
medline:
1
1
2021
entrez:
14
11
2019
Statut:
ppublish
Résumé
Nowadays most of attention regarding rotator cuff is payed to how to reduce the failure after rotator cuff surgical repair rather than how to prevent the rotator cuff tear before surgery. The etiologies of rotator cuff tear are still unclear. As we all know, the nerve system include brain, spinal cord, sensory organs and all the neurons allover our body coordinates the homoeostasis of our body. We hypothesis that the nerve injury proximal to suprascapular nerve can leads to rotator cuff degeneration even tear. Thirty-six SD rats were used. A defect on the suprascapular nerve was made on the right side and a sham surgery on the nerve (expose nerve only) at the left side. The insertion of supraspinatus tendon and supraspinatus muscle were harvested for testing. Twelve rats were sacrificed for biomechanical (six rats) and histological (six rats) properties were evaluated at 3, 6, and 9 weeks after surgery, respectively. Significant inferior biomechanical properties of rotator cuff were found in nerve injured side compared to the nerve intact side at 6-9 weeks. Significant muscle atrophy was found at nerve injured side from 3 to 9 weeks. The enthesis of nerve injured side showed significant excessive cell maturity, reduced cellularity, smaller metachromasia area and more type-III collagen especially at 9 weeks after surgery. The neuropathy proximal to suprascapular nerve can leads to rotator cuff degeneration even tear. The nerve dysfunction maybe an important etiology for rotator cuff tear.
Sections du résumé
BACKGROUND
BACKGROUND
Nowadays most of attention regarding rotator cuff is payed to how to reduce the failure after rotator cuff surgical repair rather than how to prevent the rotator cuff tear before surgery. The etiologies of rotator cuff tear are still unclear. As we all know, the nerve system include brain, spinal cord, sensory organs and all the neurons allover our body coordinates the homoeostasis of our body. We hypothesis that the nerve injury proximal to suprascapular nerve can leads to rotator cuff degeneration even tear.
METHODS
METHODS
Thirty-six SD rats were used. A defect on the suprascapular nerve was made on the right side and a sham surgery on the nerve (expose nerve only) at the left side. The insertion of supraspinatus tendon and supraspinatus muscle were harvested for testing. Twelve rats were sacrificed for biomechanical (six rats) and histological (six rats) properties were evaluated at 3, 6, and 9 weeks after surgery, respectively.
RESULTS
RESULTS
Significant inferior biomechanical properties of rotator cuff were found in nerve injured side compared to the nerve intact side at 6-9 weeks. Significant muscle atrophy was found at nerve injured side from 3 to 9 weeks. The enthesis of nerve injured side showed significant excessive cell maturity, reduced cellularity, smaller metachromasia area and more type-III collagen especially at 9 weeks after surgery.
CONCLUSIONS
CONCLUSIONS
The neuropathy proximal to suprascapular nerve can leads to rotator cuff degeneration even tear. The nerve dysfunction maybe an important etiology for rotator cuff tear.
Identifiants
pubmed: 31718907
pii: S0949-2658(19)30329-X
doi: 10.1016/j.jos.2019.09.020
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
588-594Informations de copyright
Copyright © 2019 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.