Assessment of the risk posed to Singapore by the emergence of artemisinin-resistant malaria in the Greater Mekong Subregion.
Journal
Western Pacific surveillance and response journal : WPSAR
ISSN: 2094-7313
Titre abrégé: Western Pac Surveill Response J
Pays: Philippines
ID NLM: 101558993
Informations de publication
Date de publication:
Historique:
entrez:
14
11
2019
pubmed:
14
11
2019
medline:
2
10
2020
Statut:
epublish
Résumé
To assess the public health risk to Singapore posed by the emergence of artemisinin-resistant (ART-R) malaria in the Greater Mekong Subregion (GMS). We assessed the likelihood of importation of drug-resistant malaria into Singapore and the impact on public health of its subsequent secondary spread in Singapore. Literature on the epidemiology and contextual factors associated with ART-R malaria was reviewed. The epidemiology of malaria cases in Singapore was analysed. The vulnerability and receptivity of Singapore were examined, including the connectivity with countries reporting ART-R malaria, as well as the preparedness of Singaporean health authorities. Sources of information include international journals, World Health Organization guidelines, data from the Singapore Ministry of Health and National Public Health Laboratory of the National Centre for Infectious Diseases, and the International Air Transport Association. The importation of ART-R malaria into Singapore is possible given the close proximity and significant travel volume between Singapore and the GMS countries reporting artemisinin resistance. Singapore's vulnerability is further enhanced by the presence of foreign workers from neighbouring endemic countries. Nonetheless, the overall likelihood of such an event is low based on the rarity and decreasing trend of imported malaria incidence. This risk assessment highlights the need for a continued high degree of vigilance of ART-R malaria locally and globally to minimize the risk and public health impact of drug-resistant malaria in Singapore.
Identifiants
pubmed: 31720049
doi: 10.5365/wpsar.2018.9.2.011
pii: wpsar.2019.10.2-006
pmc: PMC6831961
doi:
Substances chimiques
Antimalarials
0
Artemisinins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
6-13Informations de copyright
(c) 2019 The authors; licensee World Health Organization.
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