ORO-Dental Manifestations in West Syndrome.


Journal

Current topics in medicinal chemistry
ISSN: 1873-4294
Titre abrégé: Curr Top Med Chem
Pays: United Arab Emirates
ID NLM: 101119673

Informations de publication

Date de publication:
2019
Historique:
received: 01 05 2019
revised: 27 05 2019
accepted: 30 05 2019
pubmed: 15 11 2019
medline: 15 2 2020
entrez: 15 11 2019
Statut: ppublish

Résumé

West Syndrome is a rare epileptic encephalopathy involving infantile spasms, altered electroencephalographic pattern with hypsarrhythmia, and psychomotor development delay. It arises in paediatric patients, generally within the first year of life, in symptomatic or idiopathic form depending on the presence of hereditary features or not. In this report it is described the case of a West syndrome patient affected by multiple caries, gingival enlargement, dental eruption abnormalities, high-arched palate and MIH, treated at the dental clinic of University of Bari "Aldo Moro". West patients present with multiple oral abnormalities, including altered eruption timing, teeth agenesis, teeth shape and position abnormalities, plaque and calculus accumulation, malocclusions and bad oral habits (mouth breathing, nails biting). West Syndrome patients' oral hygiene is generally bad due to their motor difficulty and to their low compliance towards dentists, which entails general anaesthesia to perform dental treatment. West Syndrome pharmacological treatment is usually based on antiepileptic drugs and/or ACTH. These medications are well known for their ability to induce gingival enlargement, increasing the possibility of plaque accumulation and gingivitis development.

Sections du résumé

BACKGROUND BACKGROUND
West Syndrome is a rare epileptic encephalopathy involving infantile spasms, altered electroencephalographic pattern with hypsarrhythmia, and psychomotor development delay. It arises in paediatric patients, generally within the first year of life, in symptomatic or idiopathic form depending on the presence of hereditary features or not.
CASE REPORT METHODS
In this report it is described the case of a West syndrome patient affected by multiple caries, gingival enlargement, dental eruption abnormalities, high-arched palate and MIH, treated at the dental clinic of University of Bari "Aldo Moro".
DISCUSSION CONCLUSIONS
West patients present with multiple oral abnormalities, including altered eruption timing, teeth agenesis, teeth shape and position abnormalities, plaque and calculus accumulation, malocclusions and bad oral habits (mouth breathing, nails biting).
CONCLUSION CONCLUSIONS
West Syndrome patients' oral hygiene is generally bad due to their motor difficulty and to their low compliance towards dentists, which entails general anaesthesia to perform dental treatment. West Syndrome pharmacological treatment is usually based on antiepileptic drugs and/or ACTH. These medications are well known for their ability to induce gingival enlargement, increasing the possibility of plaque accumulation and gingivitis development.

Identifiants

pubmed: 31724502
pii: CTMC-EPUB-102363
doi: 10.2174/1568026619666191114122732
doi:

Substances chimiques

Anticonvulsants 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2824-2828

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Fedora Della Vella (F)

Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", Bari, Italy.

Maria Contaldo (M)

Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Naples, Italy.

Renato Fucile (R)

Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", Bari, Italy.

Francesco Panza (F)

Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari "Aldo Moro", Bari, Italy.

Vittorio Dibello (V)

Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", Bari, Italy.

Zamira Kalemaj (Z)

Department of Chemical Engineering, University of Leeds, Leeds, United Kingdom.

Rossella Ninivaggi (R)

Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", Bari, Italy.

Massimo Petruzzi (M)

Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", Bari, Italy.

Rosario Serpico (R)

Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Naples, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH