Thoracoscopic surgical case of an ectopic mediastinal parathyroid adenoma detected by chance: a case report.


Journal

BMC surgery
ISSN: 1471-2482
Titre abrégé: BMC Surg
Pays: England
ID NLM: 100968567

Informations de publication

Date de publication:
14 Nov 2019
Historique:
received: 25 09 2019
accepted: 05 11 2019
entrez: 16 11 2019
pubmed: 16 11 2019
medline: 11 2 2020
Statut: epublish

Résumé

Ectopic mediastinal parathyroid tumor (EMPT) is a rare cause of primary hyperparathyroidism (PHPT); it is difficult to resect using the cervical approach. We describe a case of using video-assisted thoracic surgery (VATS) for EMPT resection. A 67-year-old woman with a history of postoperative thyroid cancer had no symptoms. She was diagnosed with PHPT and underwent thyroid cancer surgery. She had serum calcium and intact parathyroid hormone (PTH) levels of 11.1 mg/dL and 206 pg/mL, respectively. Chest computed tomography showed a 10-mm nodule in the anterior mediastinum. Technetium-99 m methoxyisobutyl isonitrile scintigraphy showed an abnormal uptake lesion in the anterior mediastinum. She was diagnosed with PHPT caused by EMPT and underwent VATS. The pathological examination confirmed parathyroid adenoma. Her serum calcium and intact PTH levels were normal from 15 min after tumor resection. She has had no recurrence of EMPT. The VATS approach was effective for the resection of EMPT.

Sections du résumé

BACKGROUND BACKGROUND
Ectopic mediastinal parathyroid tumor (EMPT) is a rare cause of primary hyperparathyroidism (PHPT); it is difficult to resect using the cervical approach. We describe a case of using video-assisted thoracic surgery (VATS) for EMPT resection.
CASE PRESENTATION METHODS
A 67-year-old woman with a history of postoperative thyroid cancer had no symptoms. She was diagnosed with PHPT and underwent thyroid cancer surgery. She had serum calcium and intact parathyroid hormone (PTH) levels of 11.1 mg/dL and 206 pg/mL, respectively. Chest computed tomography showed a 10-mm nodule in the anterior mediastinum. Technetium-99 m methoxyisobutyl isonitrile scintigraphy showed an abnormal uptake lesion in the anterior mediastinum. She was diagnosed with PHPT caused by EMPT and underwent VATS. The pathological examination confirmed parathyroid adenoma. Her serum calcium and intact PTH levels were normal from 15 min after tumor resection. She has had no recurrence of EMPT.
CONCLUSIONS CONCLUSIONS
The VATS approach was effective for the resection of EMPT.

Identifiants

pubmed: 31727048
doi: 10.1186/s12893-019-0641-2
pii: 10.1186/s12893-019-0641-2
pmc: PMC6857287
doi:

Substances chimiques

Technetium Tc 99m Sestamibi 971Z4W1S09

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

171

Références

Gen Thorac Cardiovasc Surg. 2012 Mar;60(3):168-70
pubmed: 22419188
Exp Clin Endocrinol Diabetes. 2012 Nov;120(10):604-10
pubmed: 23174995
J Clin Endocrinol Metab. 2014 Oct;99(10):3561-9
pubmed: 25162665
Ann Thorac Surg. 2010 Jun;89(6):1750-5
pubmed: 20494022
J Surg Case Rep. 2017 Apr 20;2017(4):rjx070
pubmed: 28458875

Auteurs

Shota Mitsuboshi (S)

Department of Thoracic Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Hideyuki Maeda (H)

Department of Thoracic Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Hiroe Aoshima (H)

Department of Thoracic Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Tamami Isaka (T)

Department of Thoracic Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Takako Matsumoto (T)

Department of Thoracic Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Hiromi Onizuka (H)

Department of Surgical Pathology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Masato Kanzaki (M)

Department of Thoracic Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. kanzaki.masato@twmu.ac.jp.

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Classifications MeSH