Anti-Influenza Virus Activity of Adlay Tea Components.
Adlay
Anti-influenza virus
Daidzein
Glycitein
Naked barley
Soybean
Journal
Plant foods for human nutrition (Dordrecht, Netherlands)
ISSN: 1573-9104
Titre abrégé: Plant Foods Hum Nutr
Pays: Netherlands
ID NLM: 8803554
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
pubmed:
16
11
2019
medline:
23
2
2020
entrez:
16
11
2019
Statut:
ppublish
Résumé
Our previous study showed anti-influenza virus activity in adlay tea prepared from adlay seeds, naked barley seeds, soybean, and cassia seeds. In this study, we evaluated the anti-influenza virus activity of each component of this tea and analyzed their active ingredients. Each component was roasted and extracted in hot water; the extracts were tested for antiviral activity and their mechanisms of action were studied. All the tea components showed antiviral activity against the H1N1 and H3N2 influenza subtypes and against influenza B. The viral stages inhibited by the components were virus adsorption and replication in proliferative process, suggesting that the action mechanisms of the components might differ from those of oseltamivir acid. Of the tea components, soybean showed the strongest activity. Therefore, we analyzed its active ingredients by liquid chromatography quadruple time-of-flight mass spectrometry (LC/qTOF-MS) and daidzein and glycitein were detected as active ingredients. Here, anti-influenza virus action of glycitein was the first report.
Identifiants
pubmed: 31728799
doi: 10.1007/s11130-019-00773-3
pii: 10.1007/s11130-019-00773-3
doi:
Substances chimiques
Tea
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
538-543Subventions
Organisme : Japan Society for the Promotion of Science
ID : JP 24501017
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