Rev1 wbdR tagged vaccines against Brucella ovis.
Journal
Veterinary research
ISSN: 1297-9716
Titre abrégé: Vet Res
Pays: England
ID NLM: 9309551
Informations de publication
Date de publication:
15 Nov 2019
15 Nov 2019
Historique:
received:
05
07
2019
accepted:
23
10
2019
entrez:
16
11
2019
pubmed:
16
11
2019
medline:
3
3
2020
Statut:
epublish
Résumé
Sheep brucellosis is a worldwide extended disease caused by B. melitensis and B. ovis, two species respectively carrying smooth or rough lipopolysaccharide. Vaccine B. melitensis Rev1 is used against B. melitensis and B. ovis but induces an anti-smooth-lipopolysaccharide response interfering with B. melitensis serodiagnosis, which precludes its use against B. ovis where B. melitensis is absent. In mice, Rev1 deleted in wbkC (Brucella lipopolysaccharide formyl-transferase) and carrying wbdR (E. coli acetyl-transferase) triggered antibodies that could be differentiated from those evoked by wild-type strains, was comparatively attenuated and protected against B. ovis, suggesting its potential as a B. ovis vaccine.
Identifiants
pubmed: 31730501
doi: 10.1186/s13567-019-0714-3
pii: 10.1186/s13567-019-0714-3
pmc: PMC6858679
doi:
Substances chimiques
Amino Sugars
0
Brucella Vaccine
0
Polysaccharides
0
Vaccines, Attenuated
0
N-acetylperosamine
14131-56-7
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
95Subventions
Organisme : Ministerio de Economía y Competitividad
ID : BES-2015-075609
Organisme : Ministerio de Economía y Competitividad
ID : AGL-2014-58795-C4-1-R
Organisme : ISTUN FUNDERS
ID : Obra Social la CAIXA, "Fundaciones Caja Navarra" and "Roviralta, PROFAND, Ubesol, ACUNSA"
Organisme : ISTUN FUNDERS
ID : "Artai"
Commentaires et corrections
Type : ErratumIn
Références
PLoS One. 2015 Aug 28;10(8):e0136865
pubmed: 26317399
Clin Diagn Lab Immunol. 1999 Mar;6(2):269-72
pubmed: 10066666
Transbound Emerg Dis. 2019 Jan;66(1):505-516
pubmed: 30375177
Clin Diagn Lab Immunol. 1998 Nov;5(6):749-54
pubmed: 9801329
Vaccine. 2009 Jan 7;27(2):187-91
pubmed: 19007836
Anal Biochem. 1982 Jan 1;119(1):115-9
pubmed: 6176137
Vet Res. 2014 Jul 17;45:72
pubmed: 25029920
PLoS Negl Trop Dis. 2019 Jun 19;13(6):e0007509
pubmed: 31216271
Vaccine. 2006 Apr 5;24(15):2910-6
pubmed: 16439039
Vaccine. 2010 Apr 9;28(17):3038-46
pubmed: 19887131
Clin Vaccine Immunol. 2015 Jul;22(7):789-97
pubmed: 25947146
Vaccine. 2014 Apr 1;32(16):1877-81
pubmed: 24508034
Ann Inst Pasteur Microbiol. 1987 Jan-Feb;138(1):27-37
pubmed: 3300718
Vet Microbiol. 2011 Dec 29;154(1-2):152-5
pubmed: 21782356
PLoS Med. 2007 Dec;4(12):e317
pubmed: 18162038
Res Microbiol. 2000 Oct;151(8):655-68
pubmed: 11081580
Antimicrob Agents Chemother. 2009 Jan;53(1):298-302
pubmed: 19015361
Vet Res. 2018 Sep 5;49(1):85
pubmed: 30185220
Front Microbiol. 2018 May 25;9:1092
pubmed: 29887851
PLoS One. 2008 Jul 23;3(7):e2760
pubmed: 18648644
J Clin Microbiol. 1990 Oct;28(10):2169-74
pubmed: 2229339
Vet Res. 2004 Jan-Feb;35(1):1-38
pubmed: 15099501
Vaccine. 2009 Mar 10;27(11):1741-9
pubmed: 19186196
Vet Immunol Immunopathol. 1993 Aug;37(3-4):257-70
pubmed: 8236802
Front Microbiol. 2014 May 13;5:213
pubmed: 24860561
Infect Immun. 1990 May;58(5):1391-5
pubmed: 1691146
Nat Methods. 2005 Jun;2(6):443-8
pubmed: 15908923
Vet Clin North Am Food Anim Pract. 2011 Mar;27(1):95-104
pubmed: 21215893
Rev Sci Tech. 2013 Apr;32(1):249-61
pubmed: 23837382
Clin Diagn Lab Immunol. 2005 Jan;12(1):141-51
pubmed: 15642999
Can J Microbiol. 2015 Aug;61(8):565-74
pubmed: 26166710
Vet Immunol Immunopathol. 2016 Mar;171:81-102
pubmed: 26964721