Interleukin-18 Is a Prognostic Biomarker Correlated with CD8
Interleukin-18
immune infiltrates
melanoma
multiomic analysis
patient survival
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
15 Nov 2019
15 Nov 2019
Historique:
received:
22
10
2019
revised:
10
11
2019
accepted:
13
11
2019
entrez:
17
11
2019
pubmed:
17
11
2019
medline:
17
11
2019
Statut:
epublish
Résumé
Interleukin-18 (IL-18) is a cytokine that enhances innate and adaptive immune responses. Although there are conflicting reports about the roles of IL-18 in melanoma progression, the clinical relevance of IL-18 expression has not been comprehensively studied. In this study, we investigated IL-18 expression and its correlation with patient survival and immune cell infiltration in melanoma using cancer gene expression data publicly available through various databases.
Identifiants
pubmed: 31731729
pii: jcm8111993
doi: 10.3390/jcm8111993
pmc: PMC6912818
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : National Research Foundation of Korea
ID : 2017R1D1A1B03036390
Organisme : National Research Foundation of Korea
ID : 2017R1D1A1A02018653
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