Grey matter volume in developmental speech and language disorder.
Child
Language
MRI
Speech
VBM
Journal
Brain structure & function
ISSN: 1863-2661
Titre abrégé: Brain Struct Funct
Pays: Germany
ID NLM: 101282001
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
24
05
2019
accepted:
04
11
2019
pubmed:
17
11
2019
medline:
15
4
2020
entrez:
17
11
2019
Statut:
ppublish
Résumé
Developmental language disorder (DLD) and developmental speech disorder (DSD) are common, yet their etiologies are not well understood. Atypical volume of the inferior and posterior language regions and striatum have been reported in DLD; however, variability in both methodology and study findings limits interpretations. Imaging research within DSD, on the other hand, is scarce. The present study compared grey matter volume in children with DLD, DSD, and typically developing speech and language. Compared to typically developing controls, children with DLD had larger volume in the right cerebellum, possibly associated with the procedural learning deficits that have been proposed in DLD. Children with DSD showed larger volume in the left inferior occipital lobe compared to controls, which may indicate a compensatory role of the visual processing regions due to sub-optimal auditory-perceptual processes. Overall, these findings suggest that different neural systems may be involved in the specific deficits related to DLD and DSD.
Identifiants
pubmed: 31732792
doi: 10.1007/s00429-019-01978-7
pii: 10.1007/s00429-019-01978-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3387-3398Subventions
Organisme : National Health and Medical Research Council
ID : 607315
Organisme : National Health and Medical Research Council
ID : 1105008
Organisme : National Health and Medical Research Council
ID : 1116976
Organisme : National Health and Medical Research council
ID : 1023493
Organisme : Centre for Research Excellence
ID : 1023493