The Genomic Impact of European Colonization of the Americas.
Atlantic Slave Trade
European colonization
admixture history of the Americas
sex-biased admixture
Journal
Current biology : CB
ISSN: 1879-0445
Titre abrégé: Curr Biol
Pays: England
ID NLM: 9107782
Informations de publication
Date de publication:
02 12 2019
02 12 2019
Historique:
received:
05
07
2019
revised:
06
09
2019
accepted:
30
09
2019
pubmed:
19
11
2019
medline:
5
9
2020
entrez:
19
11
2019
Statut:
ppublish
Résumé
The human genetic diversity of the Americas has been affected by several events of gene flow that have continued since the colonial era and the Atlantic slave trade. Moreover, multiple waves of migration followed by local admixture occurred in the last two centuries, the impact of which has been largely unexplored. Here, we compiled a genome-wide dataset of ∼12,000 individuals from twelve American countries and ∼6,000 individuals from worldwide populations and applied haplotype-based methods to investigate how historical movements from outside the New World affected (1) the genetic structure, (2) the admixture profile, (3) the demographic history, and (4) sex-biased gene-flow dynamics of the Americas. We revealed a high degree of complexity underlying the genetic contribution of European and African populations in North and South America, from both geographic and temporal perspectives, identifying previously unreported sources related to Italy, the Middle East, and to specific regions of Africa.
Identifiants
pubmed: 31735679
pii: S0960-9822(19)31306-5
doi: 10.1016/j.cub.2019.09.076
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3974-3986.e4Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.