Vitamin B12 Deficiency Anemia and Polyneuropathy Due to Chronic Radiation Enteritis.
Anemia, Megaloblastic
/ drug therapy
Enteritis
/ drug therapy
Female
Gastrointestinal Diseases
/ drug therapy
Genital Neoplasms, Female
/ radiotherapy
Humans
Hypesthesia
/ drug therapy
Malabsorption Syndromes
/ etiology
Middle Aged
Polyneuropathies
/ drug therapy
Radiation Injuries
/ complications
Vitamin B 12
/ therapeutic use
Vitamin B 12 Deficiency
/ drug therapy
gynecological cancer
megaloblastic anemia
polyneuropathy
radiation enteritis
vitamin B12 deficiency
Journal
Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241
Informations de publication
Date de publication:
15 Mar 2020
15 Mar 2020
Historique:
pubmed:
19
11
2019
medline:
24
9
2020
entrez:
19
11
2019
Statut:
ppublish
Résumé
A 62-year-old Japanese woman developed numbness of the extremities and megaloblastic anemia. She had undergone total abdominal hysterectomy, whole-pelvis radiation therapy and chemotherapy for gynecological cancer 10 years before. Chronic abdominal pain, diarrhea and intermittent small-bowel obstruction had afflicted her for a long time. We diagnosed her with vitamin B12 deficiency anemia and polyneuropathy due to chronic radiation enteritis causing malabsorption. Vitamin B12 injections improved her numbness and anemia. The early diagnosis and treatment of deficiency of vitamin B12 are important. Physicians should regularly measure vitamin B12 levels and supplement vitamin B12 as needed in patients with chronic radiation enteritis.
Identifiants
pubmed: 31735792
doi: 10.2169/internalmedicine.3695-19
pmc: PMC7118398
doi:
Substances chimiques
Vitamin B 12
P6YC3EG204
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
859-861Références
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