History of Inflammatory Bowel Diseases.
bowel
inflammation
inflammatory bowel disease
interactome
therapy
ulcerative colitis
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
14 Nov 2019
14 Nov 2019
Historique:
received:
07
09
2019
revised:
02
11
2019
accepted:
12
11
2019
entrez:
20
11
2019
pubmed:
20
11
2019
medline:
20
11
2019
Statut:
epublish
Résumé
Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal mucosa and unknown etiology. In this review, we identified three main eras in the IBD history. Between the 19th and the 20th century, the primary task had been the definition of the diagnostic criteria in order to differentiate the new entity from intestinal tuberculosis. In the 20th century, an intense and prolific therapeutic research prevailed, culminating in the introduction of biological drugs in the clinical setting. Since the beginning of the 21st century, traditional definition criteria have been challenged by holistic criteria in an effort to seek a still unattained cure. Centuries of worldwide efforts on IBD etiology and therapy search have culminated in this novel strategy.
Identifiants
pubmed: 31739460
pii: jcm8111970
doi: 10.3390/jcm8111970
pmc: PMC6912289
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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