High Prevalence of Celiac Disease in Patients with Immune Thrombocytopenia.
Celiac disease
Epidemiology
Screening
Thrombocytopenia
Journal
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion
ISSN: 0971-4502
Titre abrégé: Indian J Hematol Blood Transfus
Pays: India
ID NLM: 9425818
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
27
01
2019
accepted:
03
04
2019
entrez:
20
11
2019
pubmed:
20
11
2019
medline:
20
11
2019
Statut:
ppublish
Résumé
Celiac disease (CD) is known to be associated with several autoimmune disorders. We studied the prevalence of subclinical CD among patients with immune thrombocytopenia (ITP) as compared to general population. Cases of primary ITP between the age group of 18-60 years were studied. Besides clinical examination, all patients underwent serology testing for tissue transglutaminase antibody (tTG) IgA and anti-endomysial antibodies IgA. The diagnosis of CD was made if both antibodies were positive. Healthy subjects acted as controls and underwent serological testing for tTG IgA. Seventy-nine primary ITP and 316 healthy subjects underwent serology testing for CD. Four patients of primary ITP (4/79) were positive for both serology as compared to 2 (2/316) healthy controls [odds ratio 8.37 (CI 1.50-46.47,
Identifiants
pubmed: 31741627
doi: 10.1007/s12288-019-01120-x
pii: 1120
pmc: PMC6825053
doi:
Types de publication
Journal Article
Langues
eng
Pagination
722-725Informations de copyright
© Indian Society of Hematology and Blood Transfusion 2019.
Déclaration de conflit d'intérêts
Conflict of interestAll authors declare no conflict of interest in writing this manuscript.
Références
Dig Dis Sci. 1996 Jan;41(1):83-7
pubmed: 8565771
Indian J Gastroenterol. 2001 Nov-Dec;20(6):234-6
pubmed: 11817777
Eur J Pediatr. 2002 May;161(5):284-7
pubmed: 12012226
Platelets. 2008 Jun;19(4):252-7
pubmed: 18569860
Am J Gastroenterol. 2001 Sep;96(9):2804-5
pubmed: 11569725
Blood. 2009 Mar 12;113(11):2386-93
pubmed: 19005182
J Gastroenterol Hepatol. 2011 May;26(5):894-900
pubmed: 21182543
Clin Appl Thromb Hemost. 2011 Nov-Dec;17(6):E13-6
pubmed: 20682594
South Med J. 2003 Jul;96(7):721-3
pubmed: 12940332
Scand J Gastroenterol. 2008;43(4):416-22
pubmed: 18365906
Gastroenterol Clin North Am. 2008 Jun;37(2):411-28, vii
pubmed: 18499028
Acta Haematol. 2004;111(4):211-4
pubmed: 15153713
Int Arch Allergy Immunol. 1997 Feb;112(2):140-4
pubmed: 9030093
J Paediatr Child Health. 2011 Apr;47(4):240
pubmed: 21501273
Br J Haematol. 2007 Jul;138(2):245-8
pubmed: 17542983
Dig Liver Dis. 2012 Jun;44(6):530-2
pubmed: 22497903
J Clin Gastroenterol. 1996 Oct;23(3):214-6
pubmed: 8899505
J Clin Lab Immunol. 1981 Jul;6(1):81-5
pubmed: 7196455