A molecular war: convergent and ontogenetic evidence for adaptive host manipulation in related parasites infecting divergent hosts.
behaviour manipulation
convergence
hydrophilia
mermithid
parasite
proteomics
Journal
Proceedings. Biological sciences
ISSN: 1471-2954
Titre abrégé: Proc Biol Sci
Pays: England
ID NLM: 101245157
Informations de publication
Date de publication:
20 11 2019
20 11 2019
Historique:
entrez:
21
11
2019
pubmed:
21
11
2019
medline:
17
6
2020
Statut:
ppublish
Résumé
Mermithids (phylum Nematoda) and hairworms (phylum Nematomorpha) somehow drive their arthropod hosts into water, which is essential for the worms' survival after egression. The mechanisms behind this behavioural change have been investigated in hairworms, but not in mermithids. Establishing a similar mechanistic basis for host behavioural change between these two distantly related parasitic groups would provide strong convergent evidence for adaptive manipulation and insight into how these parasites modify and/or create behaviour. Here, we search for this convergence, and also contrast changes in physiology between hosts infected with immature and mature mermithids to provide the first ontogenetic evidence for adaptive manipulation by disentangling host response and pathology from the parasite's apparent manipulative effects. We used SWATH-mass spectrometry on brains of
Identifiants
pubmed: 31744433
doi: 10.1098/rspb.2019.1827
pmc: PMC6892044
doi:
Substances chimiques
Arthropod Proteins
0
Insect Proteins
0
Proteome
0
Banques de données
figshare
['10.6084/m9.figshare.c.4722074']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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