Prevention of food allergy - skin barrier interventions.


Journal

Allergology international : official journal of the Japanese Society of Allergology
ISSN: 1440-1592
Titre abrégé: Allergol Int
Pays: England
ID NLM: 9616296

Informations de publication

Date de publication:
Jan 2020
Historique:
received: 18 10 2019
revised: 18 10 2019
accepted: 24 10 2019
pubmed: 21 11 2019
medline: 2 6 2020
entrez: 21 11 2019
Statut: ppublish

Résumé

The relationship between infant skin health and food allergy pathogenesis is the focus of intense research activity, on the basis that interventions to improve infant skin health may potentially lead to the prevention of food allergy. Current evidence does not provide conclusive findings on the mechanisms of food allergy development but does support the possibility that food allergy develops through transcutaneous sensitisation to allergenic peptides. In this article, we review the evidence for this model of food allergy development, assess strategies currently being tested for prevention of food allergy through cutaneous interventions, and identify key knowledge gaps which might be explored in future work.

Identifiants

pubmed: 31744689
pii: S1323-8930(19)30169-8
doi: 10.1016/j.alit.2019.10.005
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

3-10

Subventions

Organisme : Department of Health
ID : PB-PG-0317-20028
Pays : United Kingdom
Organisme : Department of Health
ID : TRF-2017-10-003
Pays : United Kingdom

Informations de copyright

Copyright © 2019 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

Auteurs

Maeve M Kelleher (MM)

National Heart and Lung Institute, Imperial College London, London, UK.

Lien Tran (L)

Imperial Clinical Trials Unit, Imperial College London, London, UK.

Robert J Boyle (RJ)

National Heart and Lung Institute, Imperial College London, London, UK; Centre of Evidenced Based Dermatology, University of Nottingham, Nottingham, UK. Electronic address: r.boyle@imperial.ac.uk.

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Classifications MeSH