Permanent chemotherapy-induced alopecia: awareness and attitudes among health care providers.
Adult
Alopecia
/ chemically induced
Antineoplastic Combined Chemotherapy Protocols
/ adverse effects
Attitude of Health Personnel
Awareness
Female
Health Knowledge, Attitudes, Practice
Health Personnel
/ psychology
Humans
Male
Medical Oncology
Middle Aged
Referral and Consultation
/ statistics & numerical data
Surveys and Questionnaires
Young Adult
Long-term effects of cancer treatment
Oncodermatology
Permanent chemotherapy-induced alopecia
Survey research
Survivorship
Journal
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
ISSN: 1433-7339
Titre abrégé: Support Care Cancer
Pays: Germany
ID NLM: 9302957
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
16
08
2019
accepted:
31
10
2019
pubmed:
21
11
2019
medline:
1
7
2020
entrez:
21
11
2019
Statut:
ppublish
Résumé
Reports of permanent chemotherapy-induced alopecia (PCIA) are increasing in the field of oncodermatology, but there is a dearth of information regarding how it is recognized and managed by health care providers (HCPs) across different medical specialties (dermatology, oncology, and internal medicine). A 25-question survey was designed to elicit general knowledge and awareness of PCIA, as well as attitudes about referral and treatment. Responses were collected via REDCap, a secure online application, and analyzed with descriptive statistics, chi-square, and ANOVA tests. There was a significant difference in the number of subjects who had heard of PCIA prior to starting the survey (Derm 79%, Onc 30%, IM 22%, p < 0.05). A larger percentage of dermatology and oncology HCPs knew the correct definition of the condition (alopecia persisting > 6 months) than IM (42% and 45% vs. 17%) and significantly more had encountered patients with the condition (47% and 45% vs. 17%). More providers in dermatology and IM knew how to diagnose PCIA compared with oncology (84% and 83% vs. 70%). Dermatology HCPs were the only participants who had attempted to treat patients with PCIA, and most providers believed that patients would accept similar types of treatment for PCIA. Dermatology HCPs were more likely to report higher confidence in their abilities to diagnose and manage PCIA than other providers. The results of this survey identify knowledge gaps about PCIA among health care providers. Therefore, education and multidisciplinary engagement should be pursued in order to improve awareness, diagnosis, referral, and management of PCIA as part of survivorship care.
Identifiants
pubmed: 31745696
doi: 10.1007/s00520-019-05169-2
pii: 10.1007/s00520-019-05169-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2887-2890Références
Tallon B, Blanchard E, Goldberg LJ (2010) Permanent chemotherapy-induced alopecia: case report and review of the literature. J Am Acad Dermatol 63(2):333–336. https://doi.org/10.1016/j.jaad.2009.06.063
doi: 10.1016/j.jaad.2009.06.063
pubmed: 20471136
Chon SY, Champion RW, Geddes ER, Rashid RM (2012) Chemotherapy-induced alopecia. J Am Acad Dermatol 67(1):e37–e47. https://doi.org/10.1016/j.jaad.2011.02.026
doi: 10.1016/j.jaad.2011.02.026
pubmed: 22178150
Kang D, Kim IR, Choi EK, Im YH, Park YH, Ahn JS, Lee JE, Nam SJ, Lee HK, Park JH, Lee DY, Lacouture ME, Guallar E, Cho J (2019) Permanent chemotherapy-induced alopecia in patients with breast cancer: a 3-year prospective cohort study. Oncologist 24(3):414–420. https://doi.org/10.1634/theoncologist.2018-0184
doi: 10.1634/theoncologist.2018-0184
pubmed: 30120165
Tosti A, Piraccini BM, Vincenzi C, Misciali C (2005) Permanent alopecia after busulfan chemotherapy. Br J Dermatol 152(5):1056–1058. https://doi.org/10.1111/j.1365-2133.2005.06469.x
doi: 10.1111/j.1365-2133.2005.06469.x
pubmed: 15888171
Miteva M, Misciali C, Fanti PA, Vincenzi C, Romanelli P, Tosti A (2011) Permanent alopecia after systemic chemotherapy: a clinicopathological study of 10 cases. Am J Dermatopathol 33(4):345–350. https://doi.org/10.1097/DAD.0b013e3181fcfc25
doi: 10.1097/DAD.0b013e3181fcfc25
pubmed: 21430504
Kluger N, Jacot W, Frouin E, Rigau V, Poujol S, Dereure O, Guillot B, Romieu G, Bessis D (2012) Permanent scalp alopecia related to breast cancer chemotherapy by sequential fluorouracil/epirubicin/cyclophosphamide (FEC) and docetaxel: a prospective study of 20 patients. Ann Oncol 23(11):2879–2884. https://doi.org/10.1093/annonc/mds095
doi: 10.1093/annonc/mds095
pubmed: 22571858
Prevezas C, Matard B, Pinquier L, Reygagne P (2009) Irreversible and severe alopecia following docetaxel or paclitaxel cytotoxic therapy for breast cancer. Br J Dermatol 160(4):883–885. https://doi.org/10.1111/j.1365-2133.2009.09043.x
doi: 10.1111/j.1365-2133.2009.09043.x
pubmed: 19222453
Machado M, Moreb JS, Khan SA (2007) Six cases of permanent alopecia after various conditioning regimens commonly used in hematopoietic stem cell transplantation. Bone Marrow Transplant 40(10):979–982. https://doi.org/10.1038/sj.bmt.1705817
doi: 10.1038/sj.bmt.1705817
pubmed: 17846605
Freites-Martinez A, Shapiro J, van den Hurk C, Goldfarb S, Jimenez JJ, Rossi AM, Paus R, Lacouture ME (2019) Hair disorders in cancer survivors. J Am Acad Dermatol 80(5):1199–1213. https://doi.org/10.1016/j.jaad.2018.03.056
doi: 10.1016/j.jaad.2018.03.056
pubmed: 29660423
Freites-Martinez A, Shapiro J, van den Hurk C, Goldfarb S, Jimenez J, Rossi AM, Paus R, Lacouture ME (2018) CME part 2: hair disorders in cancer survivors persistent chemotherapy-induced alopecia, persistent radiotherapy-induced alopecia, and hair growth disorders related to endocrine therapy or cancer surgery. J Am Acad Dermatol. https://doi.org/10.1016/j.jaad.2018.03.056
Ozoh OB, Awokola BI, Buist SA (2014) A survey of the knowledge of general practitioners, family physicians and pulmonologists in Nigeria regarding the diagnosis and treatment of chronic obstructive pulmonary disease. West Afr J Med 33(2):100–106
pubmed: 25236825
Jho HJ, Kim Y, Kong KA, Kim DH, Choi JY, Nam EJ, Choi JY, Koh S, Hwang KO, Baek SK, Park EJ (2014) Knowledge, practices, and perceived barriers regarding cancer pain management among physicians and nurses in Korea: a nationwide multicenter survey. PLoS One 9(8):e105900. https://doi.org/10.1371/journal.pone.0105900
doi: 10.1371/journal.pone.0105900
pubmed: 25144641
pmcid: 4140841
Kang D, Kim IR, Park YH, Im YH, Zhao D, Guallar E, Ahn JS, Cho J (2019) Impact of a topical lotion, CG428, on permanent chemotherapy-induced alopecia in breast cancer survivors: a pilot randomized double-blind controlled clinical trial (VOLUME RCT). Support Care Cancer:1–9. https://doi.org/10.1007/s00520-019-04982-z
Chan DF-MA, Ciccolini K, Samuels A, Lacouture M (2018) Impact of persistent anticancer therapy–induced alopecia on quality of life. J Am Acad Dermatol 73(3):AB160