Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis.
Animals
Apoptosis
/ genetics
Caspase 8
/ genetics
Cell Line
Cells, Cultured
Enzyme Activation
/ genetics
Gene Expression Profiling
Gene Knockout Techniques
HEK293 Cells
Humans
Inflammasomes
/ metabolism
Intestinal Mucosa
/ cytology
Keratinocytes
/ cytology
Mice
Mutation
Necroptosis
/ genetics
Pyroptosis
/ genetics
Receptor, TIE-2
/ genetics
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
18
02
2019
accepted:
15
10
2019
pubmed:
22
11
2019
medline:
14
4
2020
entrez:
22
11
2019
Statut:
ppublish
Résumé
Caspase-8 is the initiator caspase of extrinsic apoptosis
Identifiants
pubmed: 31748744
doi: 10.1038/s41586-019-1770-6
pii: 10.1038/s41586-019-1770-6
doi:
Substances chimiques
Inflammasomes
0
Receptor, TIE-2
EC 2.7.10.1
Tek protein, mouse
EC 2.7.10.1
Caspase 8
EC 3.4.22.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
683-687Références
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