Super Resolution Microscopy of SUMO Proteins in Neurons.

PSD95 neuron small ubiquitin-like modifier super resolution microscopy synapse synaptophysin

Journal

Frontiers in cellular neuroscience
ISSN: 1662-5102
Titre abrégé: Front Cell Neurosci
Pays: Switzerland
ID NLM: 101477935

Informations de publication

Date de publication:
2019
Historique:
received: 20 08 2019
accepted: 14 10 2019
entrez: 22 11 2019
pubmed: 22 11 2019
medline: 22 11 2019
Statut: epublish

Résumé

The ubiquitously expressed SUMO proteins regulate a plethora of cellular pathways and processes. While they have a predominantly nuclear localization, extranuclear roles of SUMO isoforms at the synapse have also been described, making SUMOylation one of the major post-translational regulators of nerve functions. These findings have however recently been challenged, at least for SUMO1, by the analysis of knock-in mice expressing His

Identifiants

pubmed: 31749687
doi: 10.3389/fncel.2019.00486
pmc: PMC6844275
doi:

Types de publication

Journal Article

Langues

eng

Pagination

486

Informations de copyright

Copyright © 2019 Colnaghi, Russo, Natale, Restelli, Cagnotto, Salmona, Chiesa and Fioriti.

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Auteurs

Luca Colnaghi (L)

Department of Neuroscience, Dulbecco Telethon Institute, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Luca Russo (L)

Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Carmina Natale (C)

Department of Neuroscience, Dulbecco Telethon Institute, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Elena Restelli (E)

Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Alfredo Cagnotto (A)

Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Mario Salmona (M)

Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Roberto Chiesa (R)

Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Luana Fioriti (L)

Department of Neuroscience, Dulbecco Telethon Institute, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Classifications MeSH