A review on immunohistochemical and histopathologic validation in PET-CT findings with consideration to microRNAs.
Positron Emission Tomography Computed Tomography
histopathology
immunohistochemistry
microRNAs
neoplasms
Journal
Medicine and pharmacy reports
ISSN: 2668-0572
Titre abrégé: Med Pharm Rep
Pays: Romania
ID NLM: 101742144
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
13
04
2019
accepted:
20
06
2019
entrez:
22
11
2019
pubmed:
22
11
2019
medline:
22
11
2019
Statut:
ppublish
Résumé
This review provides an overview of some of the most recent clinical trials which investigated various types of cancer and other diseases, through the use of PET-CT imaging, highlighting the use of immunohistochemical stains or conventional histopathology for the validation or contradiction of their hypothesis. Furthermore, we investigate a potential new direction of research by analyzing the upcoming role of microRNAs in disease confirmation. An extensive search of MEDLINE/PubMed and SCOPUS electronic databases was made, using the MeSH terms "positron emission tomography computed tomography" and "immunohistochemistry" as well as "SUV" and "immunohistochemistry", restricting the search by clinical trials and time period. Further searches were made for articles regarding Ki-67 and microRNAs in correlation with metabolic PET-CT uptake. Out of all 389 initial search results, 27 original articles were found relevant to the topic. Their contents were synthesized and discussed regarding the matter at hand. No relevant clinical trials involving microRNAs were found. Immunohistochemical and histopathologic results remain widely used and indispensable in modern research, concerning PET-CT validation. Possible candidates for diagnosis confirmation, in future research, may reside in the further development of microRNAs.
Identifiants
pubmed: 31750432
doi: 10.15386/mpr-1341
pii: cm-91-337
pmc: PMC6853049
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
337-345Références
J Nucl Med. 2017 Dec;58(12):1906-1912
pubmed: 28912144
Int J Gynecol Cancer. 2010 Jan;20(1):110-5
pubmed: 20130510
J Nucl Med. 2013 Apr;54(4):499-506
pubmed: 23471314
PLoS One. 2015 Jun 03;10(6):e0129028
pubmed: 26038827
J Nucl Med. 2012 Apr;53(4):538-45
pubmed: 22343504
J Nucl Med. 2016 May;57(5):672-7
pubmed: 26719378
J Nucl Med. 2013 Oct;54(10):1697-702
pubmed: 23970364
Eur J Nucl Med Mol Imaging. 2004 Jan;31(1):5-12
pubmed: 14551748
Oncotarget. 2017 Apr 25;8(17):28285-28296
pubmed: 28423698
Chirurgia (Bucur). 2013 Jul-Aug;108(4):490-7
pubmed: 23958091
Cancer Biother Radiopharm. 2003 Jun;18(3):327-37
pubmed: 12954120
Cancer Invest. 2015 Jul;33(6):246-50
pubmed: 25950983
J Cell Physiol. 2018 Jul;233(7):5200-5213
pubmed: 29219189
Eur J Nucl Med Mol Imaging. 2003 Sep;30(9):1266-9
pubmed: 12856157
Endocr Rev. 2018 Apr 1;39(2):154-191
pubmed: 29300866
J Hepatol. 2011 Oct;55(4):846-57
pubmed: 21334407
J Nucl Med. 2011 Nov;52(11):1698-703
pubmed: 21990578
Biomed Pharmacother. 2017 Dec;96:229-237
pubmed: 28987947
J Nucl Med. 2007 May;48(5):771-5
pubmed: 17475966
Ann Oncol. 2016 Apr;27(4):619-24
pubmed: 26598545
Am J Respir Crit Care Med. 2004 Oct 15;170(8):828-9
pubmed: 15475404
J BUON. 2017 Sep-Oct;22(5):1352-1359
pubmed: 29135125
Eur J Gastroenterol Hepatol. 2016 Dec;28(12):e33-e43
pubmed: 27769077
J Nucl Med. 2006 Mar;47(3):410-8
pubmed: 16513609
Acta Oncol. 2015;54(9):1408-15
pubmed: 26256482
Curr Opin Cardiol. 2017 Mar 16;:null
pubmed: 28306671
Cancer Res. 2002 Jun 15;62(12):3331-4
pubmed: 12067968
Eur Radiol. 2015 Nov;25(11):3314-21
pubmed: 25903708
Clin Nucl Med. 2013 Aug;38(8):591-6
pubmed: 23797219
J Alzheimers Dis. 2016 Dec 6;55(3):1223-1233
pubmed: 27814298
J Nucl Med. 2018 Feb;59(2):238-243
pubmed: 28775203
Cancer. 1997 Feb 15;79(4):665-7
pubmed: 9024702
J Nucl Med. 2010 Apr;51(4):543-50
pubmed: 20237034
Nucl Med Commun. 2009 Nov;30(11):831-7
pubmed: 19734817
J Nucl Med. 2016 Jan;57(1):67-9
pubmed: 26471694
Nucl Med Commun. 2014 Jan;35(1):36-43
pubmed: 24169686
Nucl Med Commun. 2016 Oct;37(10):1095-101
pubmed: 27281359
Breast Cancer Res Treat. 2011 Jul;128(1):119-26
pubmed: 21455671
Nucl Med Commun. 2004 Jan;25(1):19-27
pubmed: 15061261
Histopathology. 2000 Dec;37(6):485-500
pubmed: 11122430
Perspect Clin Res. 2016 Apr-Jun;7(2):68-74
pubmed: 27141472
J Nucl Med. 2015 Jul;56(7):1075-8
pubmed: 25999434
J Alzheimers Dis. 2016 Mar 31;52(3):863-73
pubmed: 27031469
Radiology. 2015 Dec;277(3):644-61
pubmed: 26599925
J BUON. 2014 Apr-Jun;19(2):524-9
pubmed: 24965416
Gastroenterology. 2005 Dec;129(6):2118-20; discussion 2120
pubmed: 16344083
J Nucl Med. 2016 Dec;57(12):1851-1857
pubmed: 27469355
J Surg Oncol. 2009 Dec 15;100(8):688-92
pubmed: 19731260
Expert Opin Biol Ther. 2015 Jun;15(6):773-85
pubmed: 25819175
Clujul Med. 2017;90(3):256-261
pubmed: 28781520
Eur J Nucl Med Mol Imaging. 2010 Jul;37(7):1291-9
pubmed: 20309686
Expert Rev Gastroenterol Hepatol. 2017 Feb;11(2):149-156
pubmed: 27937041
Clin Cancer Res. 2012 Oct 1;18(19):5427-37
pubmed: 22893629
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Eur J Nucl Med Mol Imaging. 2011 Jan;38(1):37-45
pubmed: 20717823
Eur J Nucl Med Mol Imaging. 2011 Jan;38(1):46-52
pubmed: 20711577
J Nucl Med. 2012 Apr;53(4):512-20
pubmed: 22343501
Nucl Med Commun. 2013 Apr;34(4):340-6
pubmed: 23407367
Nucl Med Commun. 2009 Nov;30(11):841-5
pubmed: 19773672
J Cancer Res Clin Oncol. 2008 Feb;134(2):227-36
pubmed: 17653575