Human Left Anterior Cingulate Stimulation Elicits a Reproducible Micturition Response.


Journal

Stereotactic and functional neurosurgery
ISSN: 1423-0372
Titre abrégé: Stereotact Funct Neurosurg
Pays: Switzerland
ID NLM: 8902881

Informations de publication

Date de publication:
2019
Historique:
received: 20 05 2019
accepted: 30 09 2019
pubmed: 22 11 2019
medline: 1 4 2020
entrez: 22 11 2019
Statut: ppublish

Résumé

Electrical stimulation of a brain region producing a micturition response has never previously been described in the human. This report identifies the anterior cingulate gyrus as a brain region important in the micturition response. Stereo electroencephalography was performed in a 38-year-old female with medically refractory epilepsy. The response of the left anterior cingulate from low- to high-frequency brain stimulation was tested. Stimulation within the left anterior cingulate resulted in a reproducible micturition response. The response was dependent on the frequency of stimulation (present with stimulation at 50-150 Hz and not present at 5 or 350 Hz). These results provide evidence for the presence of a region within the human left anterior cingulate gyrus involved in producing the micturition response. This may have implications in the understanding of the physiological mechanisms of willful micturition and in the treatment of bladder disorders.

Identifiants

pubmed: 31751999
pii: 000503886
doi: 10.1159/000503886
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

278-281

Informations de copyright

© 2019 S. Karger AG, Basel.

Auteurs

Sanjay Patra (S)

Department of Neurosurgery, Spectrum Health Medical Group, Grand Rapids, Michigan, USA, sanjay.patra@spectrumhealth.org.
Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA, sanjay.patra@spectrumhealth.org.

Lance Valls (L)

Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.

Gabe Heredia (G)

Department of Radiology, Spectrum Health Medical Group, Grand Rapids, Michigan, USA.

David Burdette (D)

Department of Neurosurgery, Spectrum Health Medical Group, Grand Rapids, Michigan, USA.
Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.

Konstantin Elisevich (K)

Department of Neurosurgery, Spectrum Health Medical Group, Grand Rapids, Michigan, USA.
Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.

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