Redox Regulation and Oxidative Stress: The Particular Case of the Stallion Spermatozoa.
equine
horses
oxidative stress
reactive oxygen species (ROS)
redox regulation
spermatozoa
Journal
Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981
Informations de publication
Date de publication:
19 Nov 2019
19 Nov 2019
Historique:
received:
29
09
2019
revised:
05
11
2019
accepted:
15
11
2019
entrez:
23
11
2019
pubmed:
23
11
2019
medline:
23
11
2019
Statut:
epublish
Résumé
Redox regulation and oxidative stress have become areas of major interest in spermatology. Alteration of redox homeostasis is recognized as a significant cause of male factor infertility and is behind the damage that spermatozoa experience after freezing and thawing or conservation in a liquid state. While for a long time, oxidative stress was just considered an overproduction of reactive oxygen species, nowadays it is considered as a consequence of redox deregulation. Many essential aspects of spermatozoa functionality are redox regulated, with reversible oxidation of thiols in cysteine residues of key proteins acting as an "on-off" switch controlling sperm function. However, if deregulation occurs, these residues may experience irreversible oxidation and oxidative stress, leading to malfunction and ultimately death of the spermatozoa. Stallion spermatozoa are "professional producers" of reactive oxygen species due to their intense mitochondrial activity, and thus sophisticated systems to control redox homeostasis are also characteristic of the spermatozoa in the horse. As a result, and combined with the fact that embryos can easily be collected in this species, horses are a good model for the study of redox biology in the spermatozoa and its impact on the embryo.
Identifiants
pubmed: 31752408
pii: antiox8110567
doi: 10.3390/antiox8110567
pmc: PMC6912273
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Ministerio de Ciencia, Innovación y Universidades
ID : AGL2017-83149-R
Organisme : Consejería de Empleo Empresa e Innovación del Gobierno de Extremadura
ID : IB16030 and GR18008
Références
Reprod Domest Anim. 2018 Feb;53(1):54-67
pubmed: 28833663
Asian J Androl. 2017 Jan-Feb;19(1):73-79
pubmed: 26823067
Am J Vet Res. 2000 Sep;61(9):1026-30
pubmed: 10976731
J Urol. 2018 Aug;200(2):414-422
pubmed: 29530785
Hum Reprod Update. 2015 Mar-Apr;21(2):209-27
pubmed: 25519143
FEBS Lett. 2006 Nov 13;580(26):6161-8
pubmed: 17064697
Sci Rep. 2017 Dec 19;7(1):17759
pubmed: 29259204
Redox Biol. 2013 Feb 08;1:244-57
pubmed: 24024158
Biol Reprod. 2001 Oct;65(4):1102-13
pubmed: 11566731
Cancer Commun (Lond). 2018 Apr 25;38(1):12
pubmed: 29764521
J Proteome Res. 2014 Dec 5;13(12):5670-84
pubmed: 25250979
Semin Surg Oncol. 1998 Dec;15(4):254-62
pubmed: 9829383
Curr Opin Chem Biol. 2014 Aug;21:48-55
pubmed: 24762292
Food Funct. 2019 Jun 19;10(6):3324-3333
pubmed: 31095144
Andrology. 2019 Jan;7(1):24-30
pubmed: 30225889
J Biol Chem. 2015 Jul 24;290(30):18855-64
pubmed: 26060254
Andrologia. 1979 Sep-Oct;11(5):385-91
pubmed: 517774
Theriogenology. 2018 Feb;107:149-153
pubmed: 29154176
Redox Biol. 2017 Apr;11:111-117
pubmed: 27912195
Sci Rep. 2016 Sep 16;6:33647
pubmed: 27633131
Biol Reprod. 2009 Dec;81(6):1106-11
pubmed: 19605785
Mol Cell Endocrinol. 2005 Dec 21;245(1-2):1-6
pubmed: 16274924
Int J Androl. 2003 Apr;26(2):109-14
pubmed: 12641829
Genes Dev. 2016 Dec 15;30(24):2651-2656
pubmed: 28031247
Diabetes Res Clin Pract. 2011 Jan;91(1):61-6
pubmed: 20970866
Mol Cell Endocrinol. 2006 May 16;250(1-2):66-9
pubmed: 16412557
Andrology. 2017 Mar;5(2):204-218
pubmed: 28297559
J Med Chem. 1999 Dec 16;42(25):5153-9
pubmed: 10602700
Reproduction. 2015 Mar;149(3):235-44
pubmed: 25504869
Theriogenology. 2010 Aug;74(3):458-65
pubmed: 20451990
Biol Reprod. 2016 Nov;95(5):107
pubmed: 27683266
Theriogenology. 1999 Jul 15;52(2):289-301
pubmed: 10734395
Science. 2003 Apr 25;300(5619):650-3
pubmed: 12714747
Genome Res. 2016 Aug;26(8):1034-46
pubmed: 27034506
Biol Reprod. 2009 Jun;80(6):1239-52
pubmed: 19211810
J Fish Biol. 2009 Sep;75(4):816-33
pubmed: 20738581
Biol Reprod. 2013 Jan 25;88(1):21
pubmed: 23115269
Fertil Steril. 2009 Apr;91(4):1023-34
pubmed: 18367177
Biol Reprod. 2015 May;92(5):125
pubmed: 25740544
Fertil Steril. 2010 May 1;93(7):2437-40
pubmed: 19819434
Reprod Domest Anim. 2015 Aug;50(4):529-37
pubmed: 26031351
Biochem Biophys Res Commun. 2017 Jan 15;482(3):426-431
pubmed: 28212726
J Androl. 2012 Jan-Feb;33(1):105-13
pubmed: 21436310
Chem Biol Interact. 2006 Oct 27;163(1-2):38-53
pubmed: 16970935
Reprod Biol Endocrinol. 2003 Feb 11;1:20
pubmed: 12646056
Cryobiology. 2013 Aug;67(1):84-90
pubmed: 23727067
Reprod Domest Anim. 2017 Dec;52(6):921-931
pubmed: 28815751
Asian J Androl. 2015 Jul-Aug;17(4):583-90
pubmed: 25926608
Annu Rev Biochem. 2017 Jun 20;86:715-748
pubmed: 28441057
J Biol Chem. 2007 Jan 12;282(2):1183-92
pubmed: 17105724
Biol Reprod. 2012 Nov 08;87(5):110
pubmed: 22933515
Biol Reprod. 2015 Dec;93(6):143
pubmed: 26536905
Syst Biol Reprod Med. 2017 Apr;63(2):100-112
pubmed: 28085499
J Cell Physiol. 2018 Dec;233(12):9685-9700
pubmed: 29953592
Anim Reprod Sci. 2015 Oct;161:82-8
pubmed: 26362050
Free Radic Biol Med. 2006 Aug 15;41(4):528-40
pubmed: 16863985
Biol Reprod. 2016 Aug;95(2):34
pubmed: 27335066
Biol Reprod. 2016 Mar;94(3):68
pubmed: 26792942
Cryobiology. 2018 Feb;80:26-29
pubmed: 29287896
Sci Rep. 2017 Oct 11;7(1):12994
pubmed: 29021631
Development. 2008 Feb;135(3):431-40
pubmed: 18094022
J Androl. 2009 Mar-Apr;30(2):183-9
pubmed: 18930907
J Biol Chem. 2013 Sep 13;288(37):26512-20
pubmed: 23861437
Hum Reprod. 2010 Oct;25(10):2415-26
pubmed: 20716559
Reproduction. 2015 Jan;149(1):113-23
pubmed: 25385721
Biomed Res Int. 2014;2014:902953
pubmed: 24791005
Andrology. 2015 Mar;3(2):395-407
pubmed: 25294093
Open Biol. 2016 Dec;6(12):
pubmed: 28003471
Redox Biol. 2015 Aug;5:124-139
pubmed: 25912168
Reprod Fertil Dev. 2016;28(1-2):1-10
pubmed: 27062870
Biol Reprod. 2004 Oct;71(4):1309-16
pubmed: 15189835
Reprod Domest Anim. 2011 Feb;46(1):141-8
pubmed: 20456666
Hum Reprod. 2011 Jul;26(7):1628-40
pubmed: 21546386
Reproduction. 2019 Feb 1;:null
pubmed: 30721132
Hum Reprod. 2018 Jun 15;:
pubmed: 29912414
Biol Reprod. 2019 Jul 1;101(1):208-222
pubmed: 30998234
Anim Reprod Sci. 2013 May;138(3-4):241-51
pubmed: 23567220
Reprod Domest Anim. 2010 Jun;45 Suppl 2:67-78
pubmed: 20591067
Reprod Domest Anim. 2016 Feb;51(1):18-25
pubmed: 26592367
Biol Reprod. 2011 Feb;84(2):238-47
pubmed: 20864641
Mol Hum Reprod. 2015 Jun;21(6):502-15
pubmed: 25837702
Trends Biochem Sci. 2003 Jan;28(1):32-40
pubmed: 12517450
Andrology. 2016 Mar;4(2):345-60
pubmed: 26825875
Biochim Biophys Acta. 2008 Jan;1784(1):106-15
pubmed: 17920343
J Am Chem Soc. 2014 Mar 12;136(10):3928-36
pubmed: 24579910
Mol Reprod Dev. 2005 Apr;70(4):494-503
pubmed: 15685628
Front Neurosci. 2015 Feb 09;9:23
pubmed: 25709564
Theriogenology. 2011 Mar 15;75(5):811-8
pubmed: 21144567
Theriogenology. 2016 Aug;86(3):839-49
pubmed: 27061367
Arch Biochem Biophys. 2016 Apr 1;595:140-6
pubmed: 27095231
Biol Reprod. 2015 Apr;92(4):108
pubmed: 25673561
Curr Pharm Des. 2003;9(5):419-25
pubmed: 12570819
Antioxid Redox Signal. 2015 Nov 10;23(14):1130-43
pubmed: 26154592
Int J Dev Biol. 2013;57(2-4):265-72
pubmed: 23784837
Biochemistry (Mosc). 2015 Sep;80(9):1178-85
pubmed: 26555470
Biol Reprod. 2017 Jan 1;96(1):107-121
pubmed: 28395341
Mol Hum Reprod. 2016 Feb;22(2):93-109
pubmed: 26676989
FEBS Lett. 2003 Nov 20;554(3):342-6
pubmed: 14623091
Andrology. 2013 Mar;1(2):192-205
pubmed: 23316012
Free Radic Res. 2010 Oct;44(10):1098-124
pubmed: 20836659
Fertil Steril. 1996 Dec;66(6):1012-7
pubmed: 8941071
Nat Commun. 2016 Nov 23;7:13539
pubmed: 27876811
J Biol Chem. 2005 Jul 15;280(28):26491-8
pubmed: 15901730
J Biol Chem. 2003 Nov 7;278(45):44874-85
pubmed: 12909633
Am J Vet Res. 2005 Aug;66(8):1415-9
pubmed: 16173486
Biol Reprod. 2011 Jul;85(1):9-12
pubmed: 21490245
Asian J Androl. 2015 Jul-Aug;17(4):633-9
pubmed: 25999358
Biochim Biophys Acta. 2008 Oct;1778(10):1978-2021
pubmed: 18510943
Biopolymers. 1999;52(2):65-83
pubmed: 10898853
J Reprod Fertil Suppl. 1975 Oct;(23):47-52
pubmed: 1060826
Mol Reprod Dev. 2015 Jan;82(1):58-65
pubmed: 25487823
Theriogenology. 2018 Oct 1;119:1-9
pubmed: 29958134
Nature. 1954 Aug 28;174(4426):404-5
pubmed: 13194007
Basic Clin Androl. 2014 Feb 11;24:4
pubmed: 25780579
Mol Hum Reprod. 2017 Feb 10;23(2):106-115
pubmed: 28025393
Nat Rev Mol Cell Biol. 2014 Jun;15(6):411-21
pubmed: 24854789
Mol Cell Proteomics. 2013 Feb;12(2):330-42
pubmed: 23161514
Reproduction. 2009 Jul;138(1):55-63
pubmed: 19380427
Int J Mol Sci. 2019 Jun 19;20(12):null
pubmed: 31248186
Acc Chem Res. 2014 Feb 18;47(2):646-55
pubmed: 24369694
Biol Reprod. 2016 Sep;95(3):53
pubmed: 27417910
Biol Reprod. 2002 Nov;67(5):1546-54
pubmed: 12390887
Soc Reprod Fertil Suppl. 2007;65:245-59
pubmed: 17644966
Curr Atheroscler Rep. 2007 Sep;9(3):216-21
pubmed: 18241616
J Biol Chem. 2006 Mar 3;281(9):5623-33
pubmed: 16407190
Biochemistry. 1998 Apr 21;37(16):5633-42
pubmed: 9548949
J Anim Sci. 2013 May;91(5):2158-68
pubmed: 23463557
Endocrinology. 2005 Feb;146(2):552-7
pubmed: 15550513
Biol Reprod. 2017 Jan 1;96(1):2-12
pubmed: 28395326
Int J Androl. 2012 Apr;35(2):109-24
pubmed: 21950496
Free Radic Biol Med. 2012 Aug 1;53(3):447-56
pubmed: 22634055
Biol Reprod. 2007 Apr;76(4):728-35
pubmed: 17229933
Reproduction. 2017 Mar;153(3):293-304
pubmed: 27965398
Redox Biol. 2019 Sep;26:101255
pubmed: 31247505
Soc Reprod Fertil Suppl. 2007;65:93-113
pubmed: 17644957
J Androl. 2011 Jul-Aug;32(4):394-401
pubmed: 21127310
Andrology. 2015 Mar;3(2):315-20
pubmed: 25598515
Biochim Biophys Acta. 2014 Apr;1843(4):806-14
pubmed: 24440277
Free Radic Biol Med. 2016 Feb;91:247-55
pubmed: 26708453
Reproduction. 2013 Oct 01;146(5):R163-74
pubmed: 23901129
Nature. 1946 Oct 5;158:485
pubmed: 20999112
Endocr J. 2017 Feb 27;64(2):123-131
pubmed: 28100869
Free Radic Biol Med. 2016 Nov;100:14-31
pubmed: 27085844
PLoS One. 2019 Jun 25;14(6):e0213420
pubmed: 31237882
Biol Reprod. 2013 Sep 27;89(3):72
pubmed: 23904511
PLoS One. 2019 Jul 5;14(7):e0211994
pubmed: 31276504
Andrology. 2017 Nov;5(6):1174-1182
pubmed: 28973824
Sci Rep. 2018 Jun 13;8(1):9002
pubmed: 29899461
J Biol Chem. 2003 Feb 21;278(8):5557-63
pubmed: 12482755
Mol Hum Reprod. 2013 Sep;19(9):570-80
pubmed: 23630234
Biol Reprod. 2019 Apr 1;100(4):1090-1107
pubmed: 30418487
Andrology. 2017 Jul;5(4):622-630
pubmed: 28718529
Free Radic Biol Med. 2018 Feb 20;116:123-128
pubmed: 29305108
Adv Anat Embryol Cell Biol. 2016;220:93-106
pubmed: 27194351
EMBO J. 2007 Apr 4;26(7):1749-60
pubmed: 17347651
Methods Enzymol. 2002;349:271-80
pubmed: 11912916
Biol Reprod. 2005 Jul;73(1):94-105
pubmed: 15772258
Antioxid Redox Signal. 2014 May 1;20(13):1994-2010
pubmed: 24111825
Free Radic Res. 2000 Dec;33(6):731-7
pubmed: 11237095
Biochim Biophys Acta. 2012 Aug;1817(8):1314-21
pubmed: 22421105
Biochem J. 2001 Jan 15;353(Pt 2):411-6
pubmed: 11139407
Dev Cell. 2004 Dec;7(6):801-14
pubmed: 15572124
Biol Reprod. 2015 May;92(5):121
pubmed: 25855261
Anim Reprod Sci. 2011 Aug;127(1-2):78-83
pubmed: 21821371
Asian J Androl. 2011 May;13(3):395-405
pubmed: 21540868
Reproduction. 2016 Dec;152(6):683-694
pubmed: 27798283
Curr Med Chem. 2016;23(31):3575-3606
pubmed: 27109577
Biol Reprod. 1999 Mar;60(3):733-9
pubmed: 10026124
Mol Hum Reprod. 2017 Feb 10;23(2):91-105
pubmed: 27932549
PLoS One. 2012;7(1):e30688
pubmed: 22292020
Antioxid Redox Signal. 2011 Feb 1;14(3):367-81
pubmed: 20522002
Free Radic Biol Med. 2011 Sep 15;51(6):1087-105
pubmed: 21708248
Reprod Domest Anim. 2019 Dec;54(12):1612-1620
pubmed: 31549441
Redox Biol. 2019 Sep;26:101284
pubmed: 31400697
Int J Androl. 1997;20 Suppl 3:44-9
pubmed: 9466185
Biol Reprod. 2016 Jun;94(6):133
pubmed: 27103446
Redox Biol. 2018 May;15:347-362
pubmed: 29306792
Redox Biol. 2018 Jul;17:70-88
pubmed: 29679893
Dev Cell. 2019 Jul 1;50(1):5-6
pubmed: 31265812
Mol Hum Reprod. 2004 May;10(5):355-63
pubmed: 14997001
Cytometry B Clin Cytom. 2018 Mar;94(2):302-311
pubmed: 28033647
Biol Reprod. 2015 Oct;93(4):104
pubmed: 26316064
Reproduction. 2019 May 1;:null
pubmed: 31063972
Andrology. 2013 Sep;1(5):723-30
pubmed: 23970451
Reproduction. 2009 Jul;138(1):33-43
pubmed: 19439561
Hum Reprod. 2015 Nov;30(11):2597-613
pubmed: 26345691
Biol Reprod. 1999 Jul;61(1):76-84
pubmed: 10377034
Biol Reprod. 2017 Oct 1;97(4):577-585
pubmed: 29025014
Biol Reprod. 2012 Jan 19;86(1):1-14
pubmed: 21976599
Biol Reprod. 2010 Mar;82(3):644-51
pubmed: 19846599
Hum Reprod. 2009 Sep;24(9):2061-70
pubmed: 19525298
Animal. 2018 Jun;12(s1):s27-s35
pubmed: 29882505
Hum Reprod Update. 2018 Sep 1;24(5):535-555
pubmed: 29800303
J Assist Reprod Genet. 2019 Aug;36(8):1721-1736
pubmed: 31325069
Reprod Biomed Online. 2015 Jul;31(1):100-7
pubmed: 25985994
Hum Reprod. 2018 Apr 1;33(4):553-562
pubmed: 29579272
Theriogenology. 2010 Mar 15;73(5):645-50
pubmed: 20018359
J Androl. 2011 Jul-Aug;32(4):348-55
pubmed: 21088231
Biol Reprod. 1975 Jun;12(5):641-6
pubmed: 1220831
Asian J Androl. 2015 Mar-Apr;17(2):230-5
pubmed: 25475660
Development. 2016 Jul 1;143(13):2325-33
pubmed: 27226326
Biol Reprod. 2011 Jul;85(1):128-36
pubmed: 21415139
Cell Death Dis. 2018 Jan 25;9(2):119
pubmed: 29371661
Biol Reprod. 2014 Sep;91(3):77
pubmed: 25078685
PLoS One. 2015 Sep 25;10(9):e0138777
pubmed: 26407142
Redox Biol. 2015 Aug;5:15-23
pubmed: 25796034
Zygote. 2018 Aug;26(4):251-260
pubmed: 30223916
J Androl. 2002 Sep-Oct;23(5):709-16
pubmed: 12185106