Study of the magnitude of diabetes and its associated risk factors among the tuberculosis patients of Morang, Eastern Nepal.


Journal

BMC public health
ISSN: 1471-2458
Titre abrégé: BMC Public Health
Pays: England
ID NLM: 100968562

Informations de publication

Date de publication:
21 Nov 2019
Historique:
received: 25 04 2019
accepted: 01 11 2019
entrez: 23 11 2019
pubmed: 23 11 2019
medline: 15 2 2020
Statut: epublish

Résumé

WHO addresses the infectious disease like Tuberculosis, and non- communicable disease like Diabetes among the top 10 causes of death worldwide, which collectively leads to increasing mortality and premature death especially in developing countries. Hence, the present study aims to assess the prevalence of diabetes and its associated risk factors among the tuberculosis patient of Morang, Eastern Nepal. A cross-sectional study was carried out among the 320 respondents undergoing tuberculosis treatment of Morang district. Respondents from eight randomly selected DOTS centers were selected purposively. The Fasting Blood Sugar and 2-h Post-Prandial Blood Sugar were assessed in the laboratory of respective DOTS center by the glucose oxidase method. An interview for socio-demographic and other variables was conducted using a pretested semi-structured questionnaire based on WHO-STEP Instrument for chronic disease and excerpt from DASS-21 was used for the variable stress. The prevalence of diabetes, pre-diabetic and glucose intolerance among tuberculosis patient was 11.9, 17.2, and 17.8% respectively. Additionally, the univariate analysis reported, user of tobacco products, current alcohol consumers, family history of diabetes and stress level, to have positive association with diabetes, while the multivariate analysis reported, the current alcohol consumer as the significant predictor of diabetes among the tuberculosis patient. A significant portion of the respondents were diabetic, impaired glucose tolerance and pre-diabetic, which supports the fact of diabetes being comorbid with tuberculosis. Hence, it shifts the focus on the bidirectional screening of tuberculosis and diabetes.

Sections du résumé

BACKGROUND BACKGROUND
WHO addresses the infectious disease like Tuberculosis, and non- communicable disease like Diabetes among the top 10 causes of death worldwide, which collectively leads to increasing mortality and premature death especially in developing countries. Hence, the present study aims to assess the prevalence of diabetes and its associated risk factors among the tuberculosis patient of Morang, Eastern Nepal.
METHODS METHODS
A cross-sectional study was carried out among the 320 respondents undergoing tuberculosis treatment of Morang district. Respondents from eight randomly selected DOTS centers were selected purposively. The Fasting Blood Sugar and 2-h Post-Prandial Blood Sugar were assessed in the laboratory of respective DOTS center by the glucose oxidase method. An interview for socio-demographic and other variables was conducted using a pretested semi-structured questionnaire based on WHO-STEP Instrument for chronic disease and excerpt from DASS-21 was used for the variable stress.
RESULTS RESULTS
The prevalence of diabetes, pre-diabetic and glucose intolerance among tuberculosis patient was 11.9, 17.2, and 17.8% respectively. Additionally, the univariate analysis reported, user of tobacco products, current alcohol consumers, family history of diabetes and stress level, to have positive association with diabetes, while the multivariate analysis reported, the current alcohol consumer as the significant predictor of diabetes among the tuberculosis patient.
CONCLUSION CONCLUSIONS
A significant portion of the respondents were diabetic, impaired glucose tolerance and pre-diabetic, which supports the fact of diabetes being comorbid with tuberculosis. Hence, it shifts the focus on the bidirectional screening of tuberculosis and diabetes.

Identifiants

pubmed: 31752802
doi: 10.1186/s12889-019-7891-x
pii: 10.1186/s12889-019-7891-x
pmc: PMC6873766
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1545

Références

PLoS One. 2012;7(10):e46502
pubmed: 23077512
Diabetes Metab J. 2012 Apr;36(2):108-15
pubmed: 22540046
Trop Med Int Health. 2012 Oct;17(10):1302-8
pubmed: 22830951
Acta Pharmacol Sin. 2009 Jun;30(6):784-7
pubmed: 19434055
PLoS One. 2012;7(7):e41367
pubmed: 22848473
N Am J Med Sci. 2014 Jan;6(1):30-4
pubmed: 24678474
PLoS One. 2013 Dec 18;8(12):e82660
pubmed: 24367535

Auteurs

Babita Sharma (B)

School of Public Health and Community Medicine (SPHCM), B. P. Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal. babeetasharma1@gmail.com.

Vijay Kumar Khanal (VK)

School of Public Health and Community Medicine (SPHCM), B. P. Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal.

Nilambar Jha (N)

School of Public Health and Community Medicine (SPHCM), B. P. Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal.

Prajjwal Pyakurel (P)

School of Public Health and Community Medicine (SPHCM), B. P. Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal.

Gyanu Nepal Gurung (GN)

School of Public Health and Community Medicine (SPHCM), B. P. Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal.

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