Neurologic examination in the elderly.
Alzheimer disease
Cognitive impairment
Dementia
Lewy body disease
Journal
Handbook of clinical neurology
ISSN: 0072-9752
Titre abrégé: Handb Clin Neurol
Pays: Netherlands
ID NLM: 0166161
Informations de publication
Date de publication:
2019
2019
Historique:
entrez:
23
11
2019
pubmed:
23
11
2019
medline:
17
4
2020
Statut:
ppublish
Résumé
Clinical evaluation of neurologic disorders in the elderly requires seeking a thorough history and performing an age-appropriate neurologic examination with special attention to changes that occur with normal aging. The history should be obtained from the patient as well as collateral sources close to the patient to ensure accuracy and should include contextual elements such as medical history, social, economic, and psychological background, as well as an assessment of current functional state beyond activities of daily living. The safety of the patient, including the presence of physical, psychological, and financial threats, should be addressed during the interview. The neurological examination in older adults may need to be modified to circumvent disabilities such as hearing and visual impairment. Some elements of the neurological examination are expected to be affected by the process of aging, including pupillary reactivity, presbyopia, difficulty with ocular pursuit and up-gaze, reduced or absent distal reflexes, slower motor speed, and reduced ability to tandem walk, among others. In addition to a screening neurological assessment, evaluation of older adults with a particular complaint may require additional interview queries and examination manoeuvres. Common symptoms in the elderly include cognitive difficulties, balance and gait disorders, tremors, and neuropathy. A specialized approach to patients with cognitive difficulties must include assessment of each cognitive domain, including attention, executive function, learning and memory, perceptual-motor function, and social cognition. Balance and gait are essential parts of the neurological examination, and in patients with a history of falls or mobility issues, should become a central part of the evaluation. In patient with tremors, careful observation of the tremor quality (amplitude, frequency, and alleviating/exacerbating factors such as rest, movement, and posture) can aid diagnosis. Evaluation of neuropathy includes determining modality (numbness, tingling, pain, and weakness) and the distribution of symptoms in order to localize the site of nerve injury, which can be supplemented with nerve conduction studies/electromyography, to guide further diagnostic workup and treatment. A combination of detailed history and examination often will suggest a likely underlying neurodegenerative disorder and guide further diagnostic workup to establish a specific diagnosis.
Identifiants
pubmed: 31753158
pii: B978-0-12-804766-8.00005-4
doi: 10.1016/B978-0-12-804766-8.00005-4
pmc: PMC7201860
mid: NIHMS1575059
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
73-88Subventions
Organisme : NIA NIH HHS
ID : P30 AG053760
Pays : United States
Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.
Références
JAMA. 1963 Sep 21;185:914-9
pubmed: 14044222
Adv Otorhinolaryngol. 2019;82:143-149
pubmed: 30947233
Neurology. 2016 Nov 1;87(18):1892-1898
pubmed: 27683845
Am J Med. 2018 Jun;131(6):602-607
pubmed: 29288631
Eur Neurol. 1984;23(1):17-21
pubmed: 6714274
Wien Klin Wochenschr. 2017 Feb;129(3-4):81-95
pubmed: 27770207
Nat Genet. 2019 Apr;51(4):649-658
pubmed: 30926972
J Neurosurg. 2018 Nov 1;:1-13
pubmed: 30497150
J Neurol. 2006 Jul;253(7):935-41
pubmed: 16511641
Nat Rev Neurol. 2014 Oct;10(10):554-69
pubmed: 25179257
Arch Neurol. 1994 Dec;51(12):1205-11
pubmed: 7986175
Trans Am Ophthalmol Soc. 1970;68:234-44
pubmed: 5524206
Ann Neurol. 1981 Sep;10(3):222-6
pubmed: 7294727
Med Clin North Am. 2019 Mar;103(2):203-213
pubmed: 30704677
Arch Clin Neuropsychol. 2016 Sep;31(6):506-16
pubmed: 27475282
Handb Clin Neurol. 2018;147:377-391
pubmed: 29325626
J Neurol Neurosurg Psychiatry. 2009 Jun;80(6):667-70
pubmed: 19448090
JAMA Neurol. 2014 Sep;71(9):1143-9
pubmed: 25048157
JAMA. 2015 Nov 24;314(20):2172-81
pubmed: 26599185
Age Ageing. 1995 Sep;24(5):375-81
pubmed: 8669338
J Neurol Neurosurg Psychiatry. 1997 Apr;62(4):310-8
pubmed: 9120441
Can J Neurol Sci. 1997 Feb;24(1):29-36
pubmed: 9043744
J Am Med Dir Assoc. 2016 May 1;17(5):421-5
pubmed: 26923472
Brain Lang. 2006 Jan;96(1):14-36
pubmed: 16168473
Am J Med. 1989 Feb;86(2):199-202
pubmed: 2643871
JAMA Neurol. 2015 Dec;72(12):1510-8
pubmed: 26437251
Neurology. 1993 Mar;43(3 Pt 1):563-6
pubmed: 8451002
Br Med J. 1975 May 31;2(5969):486-9
pubmed: 1148666
Continuum (Minneap Minn). 2018 Jun;24(3, BEHAVIORAL NEUROLOGY AND PSYCHIATRY):745-767
pubmed: 29851876
Ann Neurol. 2017 Oct;82(4):503-513
pubmed: 28892572
Brain Lang. 2013 Nov;127(2):106-20
pubmed: 23218686
Neuroepidemiology. 1990;9(1):27-38
pubmed: 2330069
J Neurol Neurosurg Psychiatry. 2005 Mar;76 Suppl 1:i22-30
pubmed: 15718218
Can J Aging. 2018 Sep;37(3):261-269
pubmed: 29956644
J Am Geriatr Soc. 2019 Apr;67(4):674-694
pubmed: 30693946
Arch Neurol. 1996 Jun;53(6):545-8
pubmed: 8660157
Pract Neurol. 2012 Feb;12(1):14-24
pubmed: 22258168
Neurology. 1994 Dec;44(12):2308-14
pubmed: 7991117
J R Coll Gen Pract. 1985 Apr;35(273):197
pubmed: 3989786
Adv Otorhinolaryngol. 2006;63:133-151
pubmed: 16733338
Arch Neurol. 1985 Dec;42(12):1154-7
pubmed: 4062613
Otolaryngol Clin North Am. 2018 Aug;51(4):725-740
pubmed: 29803531
J Neurol. 1991 Feb;238(1):1-5
pubmed: 2030366
Handb Clin Neurol. 2018;155:333-352
pubmed: 29891070
Continuum (Minneap Minn). 2017 Apr;23(2, Selected Topics in Outpatient Neurology):359-395
pubmed: 28375910
J Am Assoc Nurse Pract. 2016 Mar;28(3):160-9
pubmed: 25964008
Age Ageing. 1996 Nov;25(6):432-8
pubmed: 9003878