New inductive proximity sensor platform for precise localization of small colorectal tumors.


Journal

Materials science & engineering. C, Materials for biological applications
ISSN: 1873-0191
Titre abrégé: Mater Sci Eng C Mater Biol Appl
Pays: Netherlands
ID NLM: 101484109

Informations de publication

Date de publication:
Jan 2020
Historique:
received: 05 11 2018
revised: 21 08 2019
accepted: 29 08 2019
entrez: 23 11 2019
pubmed: 23 11 2019
medline: 10 4 2020
Statut: ppublish

Résumé

Location of small gastric or colorectal tumors during a laparoscopic procedure is often imprecise and can be misleading. There is a real need for a compatible and straightforward tool that can be used intraoperatively to help the surgeon in this regard. We emphasize in the present work on the fabrication of a new and innovative inductive proximity switch architecture, fully compatible with laparoscopic surgery and with direct application in precise localisation of bowel tumors. An electromagnetic detection probe optimized for laparoscopic surgery and preconditioned for sterilisation was designed and constructed. Various metallic markers designed to be attached to the gastrointestinal mucosa were used for detection by the probe, from standard endoscopic and laparoscopic haemostatic clips to other custom made tags. Experiments were performed in dry and wet-lab experimental laboratory environment using ex-vivo segments of calf's small bowel and colonic surgical specimens from human patients. The dry-lab detection range varied considerably depending on the metallic component of the tags, from 0.5 mm for the endoscopic hemostatic clip to 3.5 mm for the 0.9 mm thickness stainless-steel custom tags. The latter was actually detectable from the serosal side of the fresh colonic surgical specimens in 85% of the attempts if the scanned area was less than 150 cm

Identifiants

pubmed: 31753407
pii: S0928-4931(18)33386-1
doi: 10.1016/j.msec.2019.110146
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110146

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Vasile Bințințan (V)

Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, V. Babeş Street No. 8, 400012 Cluj-Napoca, Romania.

Adrian Calborean (A)

National Institute for Research and Development of Isotopic and Molecular Technologies, Donat 67-103, 400293 Cluj-Napoca, Romania. Electronic address: adrian.calborean@itim-cj.ro.

Mihaela Mocan (M)

Technical University Cluj Napoca, Memorandumului Street No. 28, 400114 Cluj Napoca, Romania.

Sergiu Macavei (S)

National Institute for Research and Development of Isotopic and Molecular Technologies, Donat 67-103, 400293 Cluj-Napoca, Romania.

Adrian Cordoș (A)

Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, V. Babeş Street No. 8, 400012 Cluj-Napoca, Romania.

Catalin Ciuce (C)

Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, V. Babeş Street No. 8, 400012 Cluj-Napoca, Romania.

Adriana Bințințan (A)

Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, V. Babeş Street No. 8, 400012 Cluj-Napoca, Romania.

Romeo Chira (R)

Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, V. Babeş Street No. 8, 400012 Cluj-Napoca, Romania.

Georgiana Nagy (G)

Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, V. Babeş Street No. 8, 400012 Cluj-Napoca, Romania.

Valeriu Surlin (V)

University of Medicine and Pharmacy Craiova, Petru Rares Street No 2, 200349 Craiova, Romania; University of Medicine and Pharmacy Iasi, Universitatii Street Nr.16, 700115, Iasi, Romania.

Dan Timofte (D)

University of Medicine and Pharmacy Iasi, Universitatii Street Nr.16, 700115, Iasi, Romania.

Felix Nickel (F)

University of Heidelberg, Clinic of Surgery, INF 110, 69120 Heidelberg, Germany.

Beat Mueller (B)

University of Heidelberg, Clinic of Surgery, INF 110, 69120 Heidelberg, Germany.

George Dindelegan (G)

Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, V. Babeş Street No. 8, 400012 Cluj-Napoca, Romania.

Constantin Ciuce (C)

Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, V. Babeş Street No. 8, 400012 Cluj-Napoca, Romania.

Stelian Brad (S)

Technical University Cluj Napoca, Memorandumului Street No. 28, 400114 Cluj Napoca, Romania.

Mircea Murar (M)

Technical University Cluj Napoca, Memorandumului Street No. 28, 400114 Cluj Napoca, Romania.

Bogdan Mocan (B)

Technical University Cluj Napoca, Memorandumului Street No. 28, 400114 Cluj Napoca, Romania.

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Classifications MeSH