Adolescent tuberculosis.


Journal

The Lancet. Child & adolescent health
ISSN: 2352-4650
Titre abrégé: Lancet Child Adolesc Health
Pays: England
ID NLM: 101712925

Informations de publication

Date de publication:
01 2020
Historique:
received: 27 06 2019
revised: 20 08 2019
accepted: 23 09 2019
pubmed: 23 11 2019
medline: 23 7 2020
entrez: 23 11 2019
Statut: ppublish

Résumé

Adolescence is characterised by a substantial increase in the incidence of tuberculosis, a known fact since the early 20th century. Most of the world's adolescents live in low-income and middle-income countries where tuberculosis remains common, and where they comprise a quarter of the population. Despite this, adolescents have not yet been addressed as a distinct population in tuberculosis policy or within tuberculosis treatment services, and emerging evidence suggests that current models of care do not meet their needs. This Review discusses up-to-date information about tuberculosis in adolescence, with a focus on the management of infection and disease, including HIV co-infection and rifampicin-resistant tuberculosis. We outline the progress in vaccine development and highlight important directions for future research.

Identifiants

pubmed: 31753806
pii: S2352-4642(19)30337-2
doi: 10.1016/S2352-4642(19)30337-2
pmc: PMC7291359
mid: NIHMS1557051
pii:
doi:

Substances chimiques

Antitubercular Agents 0
Tuberculosis Vaccines 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

68-79

Subventions

Organisme : Medical Research Council
ID : MR/P022081/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_EX_MR/P024270/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R005990/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UP_A900_1122
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_EX_MR/K011944/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P024270/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/K011944/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_00026/2
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R007942/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_17221
Pays : United Kingdom
Organisme : FIC NIH HHS
ID : K01 TW010829
Pays : United States
Organisme : Medical Research Council
ID : MR/R005990/2
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UP_A900/1122
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 206316/Z/17/Z
Pays : United Kingdom

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

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Auteurs

Kathryn J Snow (KJ)

Department of Paediatrics and Murdoch Children's Research Institute, University of Melbourne, Melbourne, VIC, Australia; Centre for Health Equity, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia; Centre for Adolescent Health, Royal Children's Hospital Melbourne, Melbourne, Australia.

Andrea T Cruz (AT)

Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

James A Seddon (JA)

Department of Infectious Diseases, Imperial College London, London, UK; Desmond Tutu Tuberculosis Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.

Rashida A Ferrand (RA)

Clinical Research Department, Medical Research Centre Unit, The Gambia; Biomedical Research and Training Institute, Harare, Zimbabwe.

Silvia S Chiang (SS)

Department of Pediatrics, Alpert Medical School of Brown University, Providence, RI, USA; Center for International Health Research, Rhode Island Hospital, Providence, RI, USA.

Jennifer A Hughes (JA)

Desmond Tutu Tuberculosis Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.

Beate Kampmann (B)

The Vaccine Centre, Medical Research Centre Unit, The Gambia; Vaccines & Immunity Research, Medical Research Centre Unit, The Gambia.

Steve M Graham (SM)

Department of Paediatrics and Murdoch Children's Research Institute, University of Melbourne, Melbourne, VIC, Australia; The Burnet Institute, Melbourne, VIC, Australia; International Union Against Tuberculosis and Lung Disease, Paris, France.

Peter J Dodd (PJ)

School of Health and Related Research, University of Sheffield, Sheffield, UK.

Rein M Houben (RM)

Tuberculosis Modelling Group, Tuberculosis Centre, London School of Hygiene and Tropical Medicine, London, UK; Infectious Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK.

Justin T Denholm (JT)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity University of Melbourne, University of Melbourne, Melbourne, VIC, Australia; Victorian Tuberculosis Program, Melbourne Health, Melbourne, VIC, Australia.

Susan M Sawyer (SM)

Department of Paediatrics and Murdoch Children's Research Institute, University of Melbourne, Melbourne, VIC, Australia; Centre for Adolescent Health, Royal Children's Hospital Melbourne, Melbourne, Australia.

Katharina Kranzer (K)

Clinical Research Department, Medical Research Centre Unit, The Gambia; Biomedical Research and Training Institute, Harare, Zimbabwe. Electronic address: katharina.kranzer@lshtm.ac.uk.

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Classifications MeSH