Hypertrophic Cardiomyopathy and the Brockenbrough-Braunwald-Morrow Phenomenon: A Case Report.
alcohol septal ablation
brockenbrough-braunwald-morrow phenomenon
hypertrophic cardiomyopathy
septal myectomy
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
02 Oct 2019
02 Oct 2019
Historique:
entrez:
23
11
2019
pubmed:
23
11
2019
medline:
23
11
2019
Statut:
epublish
Résumé
The Brockenbrough-Braunwald-Morrow phenomenon provides objective evidence of the existence and degree of left ventricular outflow tract (LVOT) obstruction, which can be improved with pharmacological therapy, surgical myectomy, or interventional alcohol septal ablation (ASA). This article incorporates contemporary research findings that are useful for the diagnosis and management of this entity. We present the case of a 67-year-old lady with a past medical history significant for hypertension, hyperlipidemia, and coronary artery disease. The patient presented with a complaint of functional class-3 dyspnea on exertion with associated substernal chest tightness radiating to her back that had been worsening for two days prior to admission. An echocardiogram showed left ventricular hypertrophy with septal predominance measuring 17.5 mm in end-diastole and a left ventricular ejection fraction greater than 65%. The LVOT peak gradient was elevated and a positive Brockenbrough-Braunwald-Morrow phenomenon was observed for which a septal myectomy and coronary bypass of the left internal mammary artery (LIMA) to the left anterior descending (LAD) artery were performed. The patient had an uneventful postoperative course and her symptoms improved significantly. The Brockenbrough-Braunwald-Morrow phenomenon is useful to determine the degree of LVOT and to confirm the resolution of obstruction after treatment.
Identifiants
pubmed: 31754561
doi: 10.7759/cureus.5826
pmc: PMC6827703
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e5826Informations de copyright
Copyright © 2019, Bello et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Circulation. 2006 Nov 21;114(21):2232-9
pubmed: 17088454
Ann Cardiothorac Surg. 2017 Jul;6(4):329-336
pubmed: 28944173
Circulation. 2011 Dec 13;124(24):2761-96
pubmed: 22068435
World J Cardiol. 2014 Feb 26;6(2):26-37
pubmed: 24575171
Lancet. 2013 Jan 19;381(9862):242-55
pubmed: 22874472
Cardiol Res. 2018 Jun;9(3):180-182
pubmed: 29904456
Lancet. 1995 Jul 22;346(8969):211-4
pubmed: 7616800
Catheter Cardiovasc Interv. 2008 Dec 1;72(7):1016-24
pubmed: 19021274
JAMA. 2002 Mar 13;287(10):1308-20
pubmed: 11886323
Methodist Debakey Cardiovasc J. 2014 Jan-Mar;10(1):34-7
pubmed: 24932361
JAMA Cardiol. 2016 Jun 1;1(3):324-32
pubmed: 27438114
Yale J Biol Med. 2017 Sep 25;90(3):433-448
pubmed: 28955182
J Am Coll Cardiol. 2001 Dec;38(7):1994-2000
pubmed: 11738306