The contribution of sleep to social inequalities in cardiovascular disorders: a multi-cohort study.
Cardiovascular disorders
Life-course
Mediation
Sleep duration
Socioeconomic status
Journal
Cardiovascular research
ISSN: 1755-3245
Titre abrégé: Cardiovasc Res
Pays: England
ID NLM: 0077427
Informations de publication
Date de publication:
01 07 2020
01 07 2020
Historique:
received:
04
06
2019
revised:
28
08
2019
accepted:
30
10
2019
pubmed:
23
11
2019
medline:
9
2
2021
entrez:
23
11
2019
Statut:
ppublish
Résumé
Sleep disturbances exhibit a strong social patterning, and inadequate sleep has been associated with adverse health outcomes, including cardiovascular disorders (CVD). However, the contribution of sleep to socioeconomic inequalities in CVD is unclear. This study pools data from eight European cohorts to investigate the role of sleep duration in the association between life-course socioeconomic status (SES) and CVD. We used cross-sectional data from eight European cohorts, totalling 111 205 participants. Life-course SES was assessed using father's and adult occupational position. Self-reported sleep duration was categorized into recommended (6-8.5 h/night), long (>8.5 h/night), and short (<6 h/night). We examined two cardiovascular outcomes: coronary heart disease (CHD) and stroke. Main analyses were conducted using pooled data and examined the association between life-course SES and CVD, and the contribution of sleep duration to this gradient using counterfactual mediation. Low father's occupational position was associated with an increased risk of CHD (men: OR = 1.19, 95% CI [1.04; 1.37]; women: OR = 1.25, 95% CI [1.02; 1.54]), with marginal decrease of the gradient after accounting for adult occupational position (men: OR = 1.17, 95% CI [1.02; 1.35]; women: OR = 1.22, 95% CI [0.99; 1.52]), and no mediating effect by short sleep duration. Low adult occupational position was associated with an increased risk of CHD in both men and women (men: OR = 1.48, 95% CI [1.14; 1.92]; women: OR = 1.53, 95% CI [1.04; 2.21]). Short sleep duration meaningfully contributed to the association between adult occupational position and CHD in men, with 13.4% mediation. Stroke did not exhibit a social patterning with any of the variables examined. This study suggests that inadequate sleep accounts to a meaningful proportion of the association between adult occupational position and CHD, at least in men. With sleep increasingly being considered an important cardiovascular risk factor in its own terms, our study additionally points to its potential role in social inequalities in cardiovascular disease.
Identifiants
pubmed: 31754700
pii: 5634171
doi: 10.1093/cvr/cvz267
pmc: PMC7425783
doi:
Types de publication
Comparative Study
Journal Article
Multicenter Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
1514-1524Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL036310
Pays : United States
Organisme : Medical Research Council
ID : MR/R024227/1
Pays : United Kingdom
Organisme : NIA NIH HHS
ID : R37 AG013196
Pays : United States
Organisme : Medical Research Council
ID : MR/S011676/1
Pays : United Kingdom
Organisme : NIA NIH HHS
ID : R01 AG017644
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG013196
Pays : United States
Organisme : Medical Research Council
ID : MR/S019669/1
Pays : United Kingdom
Commentaires et corrections
Type : CommentIn
Informations de copyright
Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.
Références
Sleep. 2006 Aug;29(8):1063-7
pubmed: 16944675
Int J Epidemiol. 2013 Dec;42(6):1640-8
pubmed: 23143611
Sleep. 2006 Jul;29(7):881-9
pubmed: 16895254
Ann N Y Acad Sci. 1999;896:254-61
pubmed: 10681902
Sleep. 2006 Jul;29(7):878-9
pubmed: 16895253
Am J Public Health. 2002 Aug;92(8):1295-8
pubmed: 12144987
JAMA. 1993 Jun 23-30;269(24):3140-5
pubmed: 8505817
Sleep. 2004 May 1;27(3):440-4
pubmed: 15164896
Psychol Methods. 2013 Jun;18(2):137-50
pubmed: 23379553
Int J Epidemiol. 2005 Apr;34(2):251-6
pubmed: 15576467
J Epidemiol Community Health. 2003 Oct;57(10):778-83
pubmed: 14573579
Ann N Y Acad Sci. 2010 Feb;1186:146-73
pubmed: 20201872
Health Place. 2009 Dec;15(4):1006-13
pubmed: 19447667
J Public Health (Oxf). 2006 Mar;28(1):63-70
pubmed: 16287708
Prev Med. 2015 Feb;71:12-9
pubmed: 25482420
BMC Public Health. 2010 Aug 12;10:479
pubmed: 20704723
Am J Epidemiol. 2008 Dec 15;168(12):1353-64
pubmed: 18945686
Behav Sleep Med. 2013 Apr;11(2):144-58
pubmed: 23136841
J Epidemiol Community Health. 2006 Jan;60(1):7-12
pubmed: 16361448
Prog Cardiovasc Dis. 2009 Jan-Feb;51(4):294-302
pubmed: 19110131
J Clin Epidemiol. 1990;43(1):87-91
pubmed: 2319285
Am J Respir Crit Care Med. 2002 Jul 15;166(2):159-65
pubmed: 12119227
Arch Intern Med. 2003 Jan 27;163(2):205-9
pubmed: 12546611
Sleep. 2011 Apr 01;34(4):509-18
pubmed: 21461330
Int J Epidemiol. 2015 Jun;44(3):801-9
pubmed: 25212479
PLoS Med. 2011 Feb;8(2):e1000419
pubmed: 21364974
Int J Methods Psychiatr Res. 2011 Mar;20(1):40-9
pubmed: 21499542
J Epidemiol Community Health. 2003 Feb;57(2):147-53
pubmed: 12540692
Hypertension. 2000 May;35(5):1173-5
pubmed: 10818083
J Am Coll Cardiol. 2007 Feb 6;49(5):565-71
pubmed: 17276180
Lancet. 2017 Mar 25;389(10075):1229-1237
pubmed: 28159391
Psychoneuroendocrinology. 1988;13(3):233-43
pubmed: 3406323
J Epidemiol Community Health. 2001 May;55(5):301-7
pubmed: 11297647
Eur Heart J. 2008 May;29(10):1316-26
pubmed: 18256043
Int J Epidemiol. 2015 Feb;44(1):77-77g
pubmed: 25422284
Behav Sleep Med. 2010;8(4):219-30
pubmed: 20924835
Ann Epidemiol. 2007 Dec;17(12):948-55
pubmed: 17855122
Epidemiology. 2008 Nov;19(6):838-45
pubmed: 18854708
J Clin Epidemiol. 1989;42(3):245-56
pubmed: 2709082
J Epidemiol Community Health. 1982 Dec;36(4):294-7
pubmed: 7166686
Arch Intern Med. 2006 Sep 18;166(16):1689-92
pubmed: 16983045
Eur J Public Health. 2014 Dec;24(6):968-73
pubmed: 24280873
Sleep Med. 2015 Apr;16(4):469-76
pubmed: 25777484
Soc Sci Med. 2010 Sep;71(5):1027-36
pubmed: 20621406
Sleep Med. 2010 May;11(5):470-8
pubmed: 20388566
Sleep. 2011 Nov 01;34(11):1487-92
pubmed: 22043119
PLoS Med. 2013;10(7):e1001479
pubmed: 23843750
PLoS One. 2017 May 30;12(5):e0178071
pubmed: 28557991
Curr Cardiol Rep. 2017 Sep 19;19(11):110
pubmed: 28929340
Prev Med. 2018 Aug;113:15-31
pubmed: 29752959
Psychoneuroendocrinology. 2016 May;67:76-85
pubmed: 26881833