CCR9 signaling in dendritic cells drives the differentiation of Foxp3
Animals
Cell Differentiation
/ immunology
Colitis
/ immunology
Dendritic Cells
/ immunology
Hypersensitivity
/ immunology
Immunoglobulin E
/ immunology
Inflammation
/ immunology
Intestines
/ immunology
Mice
Mice, Inbred C57BL
Receptors, CCR
/ immunology
Signal Transduction
/ immunology
T-Lymphocytes, Regulatory
/ immunology
CCL25
CCR9
Foxp3
dendritic cells
mucosal tolerance
Journal
European journal of immunology
ISSN: 1521-4141
Titre abrégé: Eur J Immunol
Pays: Germany
ID NLM: 1273201
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
29
07
2019
revised:
11
10
2019
accepted:
20
11
2019
pubmed:
23
11
2019
medline:
1
8
2020
entrez:
23
11
2019
Statut:
ppublish
Résumé
The chemokine receptor CCR9 and its only known ligand CCL25 play an important role in gut inflammation and autoimmune colitis. The function of CCR9-CCL25 in the migration of immune cells is well characterized. However, its role in the immune cell differentiation is mostly not known. Using dextran sodium sulfate (DSS)-induced gut inflammation model, we showed that CCR9
Identifiants
pubmed: 31755547
doi: 10.1002/eji.201948327
doi:
Substances chimiques
CC chemokine receptor 9
0
Receptors, CCR
0
Immunoglobulin E
37341-29-0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
404-417Subventions
Organisme : Department of Science and Technology, Ministry of Science and Technology
Pays : International
Organisme : Science and Engineering Research Board
ID : PDF/2015/000792
Pays : International
Organisme : Department of Science and Technology, Government of India
Pays : International
Organisme : Department of Biotechnology, Ministry of Science and Technology
ID : BT/PR14156/BRB/10/1515/2016
Pays : International
Organisme : Department of Biotechnology, Ministry of Science and Technology
ID : BT/PR15533/MED/30/1616/2015
Pays : International
Organisme : Department of Biotechnology , Ministry of Science and Technology
ID : BT/PR14156/BRB/10/1515/2016
Pays : International
Organisme : Department of Biotechnology , Ministry of Science and Technology
ID : BT/PR15533/MED/30/1616/2015
Pays : International
Informations de copyright
© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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