Biosecurity Threat Posed by Botulinum Toxin.


Journal

Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765

Informations de publication

Date de publication:
20 11 2019
Historique:
received: 26 09 2019
revised: 03 11 2019
accepted: 13 11 2019
entrez: 24 11 2019
pubmed: 24 11 2019
medline: 18 11 2020
Statut: epublish

Résumé

The deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as unconventional weapons. Botulinum neurotoxin (BoNT) is one such biological threat, characterized by an extremely low lethal dose, high morbidity and mortality when appropriately disseminated, and the capacity to cause panic and social disruption. This paper addresses the risks of a potential release of the botulinum neurotoxin and summarizes the relevant aspects of the threat.

Identifiants

pubmed: 31757074
pii: toxins11120681
doi: 10.3390/toxins11120681
pmc: PMC6950065
pii:
doi:

Substances chimiques

Chemical Warfare Agents 0
Botulinum Toxins EC 3.4.24.69

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Orlando Cenciarelli (O)

European Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, Sweden.

Paul William Riley (PW)

European Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, Sweden.

Agoritsa Baka (A)

European Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, Sweden.

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Classifications MeSH