Anaphylaxis for Internists: Definition, Evaluation, and Management, with a Focus on Commonly Encountered Problems.

Anaphylaxis Antibiotic allergy (including penicillin and cephalosporin β-lactams) Desensitization Epinephrine Graded challenge (test dose) Meta-analysis Type I hypersensitivity (immediate hypersensitivity) Urticaria and pseudoallergy

Journal

The Medical clinics of North America
ISSN: 1557-9859
Titre abrégé: Med Clin North Am
Pays: United States
ID NLM: 2985236R

Informations de publication

Date de publication:
Jan 2020
Historique:
entrez: 24 11 2019
pubmed: 24 11 2019
medline: 4 12 2019
Statut: ppublish

Résumé

Anaphylaxis is an acute systemic allergic reaction that can be life threatening. In adults, the most common causes of anaphylaxis are foods, drugs, and insect stings. This article reviews the definition, classification, evaluation, differential diagnosis, prognosis, complications, and management of anaphylaxis. Tailored for internists, the article focuses on anaphylactic medication allergies. It provides a guide to optimally evaluate and manage patients with antibiotic allergy using a simple, rapid risk stratification technique, graded antibiotic challenge (test dose), and/or allergist-guided drug desensitization. It also reviews other causes of anaphylaxis that internists are likely to encounter, and an approach to their management.

Identifiants

pubmed: 31757236
pii: S0025-7125(19)30083-5
doi: 10.1016/j.mcna.2019.08.007
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

25-44

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Derek K Chu (DK)

Department of Medicine, McMaster University, 1200 Main Street West, HSC-3V49, Hamilton, Ontario L8N 3Z5, Canada. Electronic address: chudk@mcmaster.ca.

David J McCullagh (DJ)

Department of Medicine, McMaster University, 1200 Main Street West, HSC-3V49, Hamilton, Ontario L8N 3Z5, Canada.

Susan Waserman (S)

Department of Medicine, McMaster University, 1200 Main Street West, HSC-3V49, Hamilton, Ontario L8N 3Z5, Canada. Electronic address: waserman@mcmaster.ca.

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