Outcome of patients with breast cancer in the oldest old (≥80 years).
Age
Breast cancer
Elderly
Prognosis
Journal
European journal of obstetrics, gynecology, and reproductive biology
ISSN: 1872-7654
Titre abrégé: Eur J Obstet Gynecol Reprod Biol
Pays: Ireland
ID NLM: 0375672
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
09
06
2019
revised:
11
11
2019
accepted:
12
11
2019
pubmed:
25
11
2019
medline:
13
11
2020
entrez:
25
11
2019
Statut:
ppublish
Résumé
In the present study, we present a large institutional study to determine the influence of age≥ 80 years on breast cancer presentation and prognosis. The study is a retrospective analysis of our prospectively maintained breast cancer database study using data from of women managed from January 2007 through December 2013. Clinicopathologic characteristics were correlated with outcomes according to age (<80 years and ≥ 80 years). During the study period, 2083 women with invasive breast cancer were included of which 160 women aged ≥ 80 years (7.7 %). Overall survival was lower in the oldest old than in younger counterparts (p < 0.0001) as was distant metastasis free survival (p = 0.004). Differences in management included more radical surgeries and less chemotherapy and radiotherapy in case of age≥ 80 years. By multivariate analysis, age ≥ 80 years was an independent predictive factor of poor overall survival. In the present study, age ≥ 80 years was an independent predictive factor of poor overall survival.
Identifiants
pubmed: 31760264
pii: S0301-2115(19)30523-8
doi: 10.1016/j.ejogrb.2019.11.009
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
66-70Informations de copyright
Copyright © 2019. Published by Elsevier B.V.