Human Milk Microbiota: Transferring the Antibiotic Resistome to Infants.
Antibiotic resistance
Antibiotic resistance genes
Breast milk microbiota
Infant gut microbiota
Resistome
Journal
Indian journal of microbiology
ISSN: 0046-8991
Titre abrégé: Indian J Microbiol
Pays: India
ID NLM: 0374703
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
11
08
2019
accepted:
30
08
2019
entrez:
26
11
2019
pubmed:
26
11
2019
medline:
26
11
2019
Statut:
ppublish
Résumé
Commensal bacterial population is believed to be a reservoir for antibiotic resistance genes (ARGs). The infant gut microbiota has relatively higher abundance of ARGs than the adults. These genes can get transferred from commensals to pathogens by horizontal gene transfer, which magnifies the spectrum of antibiotic resistance in the environment. The presence of ARGs in neo-nates and infants, with no prior antibiotic exposure, questions their origin in the naïve commensal population. Breast milk microbiota that is responsible for the initial seeding of infant gut microbiota has also been found to harbour a vast array of ARGs. This review discusses the recent findings that indicate the potential of breast milk microbiota to act as a vehicle for transmission of ARGs to infants.
Identifiants
pubmed: 31762502
doi: 10.1007/s12088-019-00824-y
pii: 824
pmc: PMC6842368
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
410-416Informations de copyright
© Association of Microbiologists of India 2019.
Déclaration de conflit d'intérêts
Conflict of interestThe authors declare that they have no conflict of interest.
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