Crocetin promotes angiogenesis in human endothelial cells through PI3K-Akt-eNOS signaling pathway.

VEGFR-2- Akt-eNOS signaling angiogenesis crocetin human endothelial cells migration tube formation

Journal

EXCLI journal
ISSN: 1611-2156
Titre abrégé: EXCLI J
Pays: Germany
ID NLM: 101299402

Informations de publication

Date de publication:
2019
Historique:
received: 15 02 2019
accepted: 14 10 2019
entrez: 26 11 2019
pubmed: 26 11 2019
medline: 26 11 2019
Statut: epublish

Résumé

Previous studies proved the pro-angiogenic effect of Crocetin, a natural carotenoid dicarboxylic acid, in both

Identifiants

pubmed: 31762720
doi: 10.17179/excli2019-1175
pii: 2019-1175
pii: Doc936
pmc: PMC6868919
doi:

Types de publication

Journal Article

Langues

eng

Pagination

936-949

Informations de copyright

Copyright © 2019 Nasirzadeh et al.

Références

J Clin Invest. 1999 May;103(9):1231-6
pubmed: 10225965
J Mol Med (Berl). 1995 Jul;73(7):333-46
pubmed: 8520966
Fitoterapia. 2011 Oct;82(7):997-1002
pubmed: 21741458
Cell Physiol Biochem. 2018;46(2):765-780
pubmed: 29621746
Curr Neurovasc Res. 2012 May;9(2):102-9
pubmed: 22475394
Arch Pharm Res. 2008 Mar;31(3):357-63
pubmed: 18409050
Int J Mol Med. 2019 Feb;43(2):956-966
pubmed: 30569175
Arq Bras Cardiol. 2017 Jul;109(1):54-62
pubmed: 28678929
Oxid Med Cell Longev. 2015;2015:105135
pubmed: 26273419
Eur J Pharmacol. 2012 Jan 15;674(2-3):391-6
pubmed: 21925167
Kidney Int. 2005 Oct;68(4):1648-59
pubmed: 16164642
Biochem Biophys Res Commun. 2010 Jan 1;391(1):254-60
pubmed: 19917268
Eur J Pharmacol. 2011 Jan 10;650(1):110-9
pubmed: 20951131
Biotechnol Bioeng. 2017 Dec;114(12):2920-2930
pubmed: 28782793
Nat Med. 1995 Jan;1(1):27-31
pubmed: 7584949
N Engl J Med. 1971 Nov 18;285(21):1182-6
pubmed: 4938153
Pharmacol Res. 2006 Oct;54(4):268-74
pubmed: 16899372
Ann Neurol. 2007 Jul;62(1):49-58
pubmed: 17557352
J Cardiovasc Thorac Res. 2016;8(3):102-106
pubmed: 27777694
Biochem Biophys Res Commun. 2008 Nov 14;376(2):404-8
pubmed: 18789310
Planta Med. 2011 Jan;77(2):146-51
pubmed: 20803418
Food Chem Toxicol. 2013 Aug;58:340-6
pubmed: 23702325
Front Biosci. 2006 Jan 01;11:818-29
pubmed: 16146773
Cell Physiol Biochem. 2016;40(3-4):443-452
pubmed: 27889767

Auteurs

Mahdieh Nasirzadeh (M)

Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Yousef Rasmi (Y)

Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Cellular and Molecular Research Center, Urmia University of Medical Sciences, Urmia, Iran.

Reza Rahbarghazi (R)

Department of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Fatemeh Kheradmand (F)

Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Mojtaba Karimipour (M)

Department of Anatomy, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Pornanong Aramwit (P)

Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phaya Thai Road, Phatumwan, Bangkok 10330, Thailand.

Maryam Astinfeshan (M)

Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Zafar Gholinejad (Z)

Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Behrokh Daeihasani (B)

Department of Biology, Payame Noor University, P.O.Box 19395-3697, Tehran, Iran.

Ehsan Saboory (E)

Neuroscience Research Center, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Alireza Shirpoor (A)

Department of Physiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Aysa Rezabakhsh (A)

Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.

Elmira Zolali (E)

Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

Naser Khalaji (N)

Department of Physiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Classifications MeSH