Strain elastography for noninvasive assessment of liver fibrosis: A prospective study with histological comparison.
Liver
liver fibrosis
real-time elastography
strain elastography
ultrasound
Journal
Ultrasound (Leeds, England)
ISSN: 1742-271X
Titre abrégé: Ultrasound
Pays: United States
ID NLM: 101244122
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
06
03
2019
accepted:
13
06
2019
entrez:
26
11
2019
pubmed:
26
11
2019
medline:
26
11
2019
Statut:
ppublish
Résumé
The aim of this study was to prospectively evaluate the diagnostic performance of strain elastography for the assessment of liver fibrosis in patients with chronic liver disease using Ishak (0-6) histology stage as a reference standard. Ninety-eight consecutive patients with suspected chronic liver disease scheduled for liver biopsy (n = 78) or histologically confirmed cirrhosis (n = 20) were enrolled. Liver fibrosis Index (LF Index) calculated by strain elastography, liver stiffness by transient elastography and serum fibrosis markers (aspartate aminotransferase-to-platelet ratio index and King's Score) were measured. Spearman's correlation coefficient between the LF Index, liver stiffness, serum fibrosis markers and fibrosis stage were calculated and compared using areas under the receiver-operating characteristics (AUROCs) curves. Among 73 patients who underwent strain elastography, there was weak correlation between fibrosis stage and the LF Index (Spearman's: ρ = 0.385 for Ishak score;
Identifiants
pubmed: 31762783
doi: 10.1177/1742271X19862836
pii: 10.1177_1742271X19862836
pmc: PMC6851718
doi:
Types de publication
Journal Article
Langues
eng
Pagination
262-271Informations de copyright
© The British Medical Ultrasound Society 2019.
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