Efficacy of continuous ingestion of dewaxed brown rice on the cognitive functions of the residents of elderly welfare facilities: A pilot test using crossover trial.

brown rice cognitive function dewaxed brown rice elderly lipopolysaccharide

Journal

Food science & nutrition
ISSN: 2048-7177
Titre abrégé: Food Sci Nutr
Pays: United States
ID NLM: 101605473

Informations de publication

Date de publication:
Nov 2019
Historique:
received: 29 01 2019
revised: 31 07 2019
accepted: 12 08 2019
entrez: 26 11 2019
pubmed: 26 11 2019
medline: 26 11 2019
Statut: epublish

Résumé

Compared with regular brown rice, dewaxed brown rice (DBR), prepared by excluding only the wax layer in the outermost layer of brown rice using a new rice milling technique, has improved water absorbency, digestibility, and taste. Dewaxed brown rice has a nutritional value close to that of brown rice and contains a large amount of lipopolysaccharides (LPS), which are known to improve the cognitive function of mice. In this study, we examined the effect of continuous DBR ingestion on the cognitive function of elderly people. A crossover comparison test was performed, in which elderly people who moved into an elderly welfare facility were divided into two groups and ingested DBR or polished white rice for three meals a day for 6 months, followed by a change in test meals for the next 6 months. Cognitive function was assessed using Revised Hasegawa's Dementia Scale (HDS-R) before starting the test and 6 months after ingesting each test meal. No subjects withdrew or discontinued DBR intake during the study period, and all subjects continued the test for 6 months. In subjects with low cognitive function (defined as subjects with HDS-R total score of ≥1 but <10 at the start of the study), there was a significant association between continuous DBR ingestion and cognitive function improvement (increase in total HDS-R score). Our findings suggest that the long-term DBR ingestion as a staple food could be useful for preventing cognitive decline in elderly; it offers an easily implemented option as a daily diet for preventing cognitive decline.

Identifiants

pubmed: 31763002
doi: 10.1002/fsn3.1202
pii: FSN31202
pmc: PMC6848844
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3520-3526

Informations de copyright

© 2019 The Authors. Food Science & Nutrition published by Wiley Periodicals, Inc.

Déclaration de conflit d'intérêts

Toshiyuki Saika is an employee of Toyo Rice Corp. All other authors declared no competing interests.

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Auteurs

Maya Uenobe (M)

Department of Food and Health Sciences Faculty of Health and Human Development The University of Nagano Nagano Japan.
Course of Nutrition Management Graduate School of Human Life Science Nagoya University of Economics Aich Japan.

Toshiyuki Saika (T)

Toyo Rice Corporation Wakayama Japan.

Natsumi Waku (N)

Course of Nutrition Management Graduate School of Human Life Science Nagoya University of Economics Aich Japan.
Social Welfare Corporation Tanpopo Welfare Association TSURU no Sato Special Nursing Home for the Elderly Aich Japan.

Masae Ohno (M)

Social Welfare Corporation Nishikasugai Welfare Association Heiann no Sato Special Nursing Home for the Elderly Aich Japan.

Hiroyuki Inagawa (H)

Research Institute for Healthy Living Niigata University of Pharmacy and Applied Life Sciences Niigata Japan.
Control of Innate Immunity, Technology Research Association Kagawa Japan.

Classifications MeSH